2 research outputs found
Strawberry Ellagitannins Thwarted the Positive Effects of Dietary Fructooligosaccharides in Rat Cecum
Forty-eight
male Wistar rats were fed diets containing low (0.051%
of diet) or high (0.153% of diet) levels of an ellagitannin-rich (ET)
strawberry extract with dietary fructooligosaccharides (FOS) or cellulose
(CEL) for 4 weeks. The in vivo study demonstrated that some positive
changes in the cecal metabolism resulting from the ingestion of a
diet enriched only with FOS were completely or slightly suppressed
by the dietary ET. In particular, the pH value (7.21 vs 7.36), short-chain
fatty acid production (41.2 vs 30.0 μmol/100g BW), and β-glucuronidase
activity (20.2 vs 15.7 μmol/h/g) in the cecum of rats fed with
FOS were affected upon the addition of the ET extract. Dietary FOS
caused higher metabolism of the tested ET strawberry extract in the
gastrointestinal tract of rats. Moreover, the systemic effect of the
supplements when consumed together showed undesired serum HDL-cholesterol
decrease (0.78 vs 1.02 mmol/L in the treatment with FOS only)