3,599 research outputs found

    OMV Servicing Missions from Space Station

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    \u27!he Orbital Maneuvering Vehicle (OMV) will provide a means of bringing large observatories to the Space station for servicing and redeployment to their operating altitudes. However, there are many constraints which must be met in mission planning. \u27!he missions must be designed so that propellant consumption is within the usable allowance, but contingency operations can still be accomplished. \u27!he vehicle was designed specifically to accommodate such missions, with emphasis upon servicing the Hubble Space Telescope. \u27!he OMV has been designed for operations from the Shuttle Orbiter and the Space Station. It will readily accommodate basing at the Space Station and executing observatory retrieval and redeployment missions. Mission profiles have been designed which allow retrieval with contengency hold before descent, and which allow contengency return of the observatory if it fails to reactivate properly. This capability will be a major addition to the Space Transportation System and will increase the utility of the Space Station

    Book Reviews

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    From mice to humans: Developments in cancer immunoediting

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    Cancer immunoediting explains the dual role by which the immune system can both suppress and/or promote tumor growth. Although cancer immunoediting was first demonstrated using mouse models of cancer, strong evidence that it occurs in human cancers is now accumulating. In particular, the importance of CD8+ T cells in cancer immunoediting has been shown, and more broadly in those tumors with an adaptive immune resistance phenotype. This Review describes the characteristics of the adaptive immune resistance tumor microenvironment and discusses data obtained in mouse and human settings. The role of other immune cells and factors influencing the effector function of tumor-specific CD8+ T cells is covered. We also discuss the temporal occurrence of cancer immunoediting in metastases and whether it differs from immunoediting in the primary tumor of origin

    CCD photometry of the nuclei of three supergiant elliptical galaxies - Evidence for a supermassive object in the center of the radio galaxy NGC 6251

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    We have analyzed charged coupled device (CCD) photometry in the g and r bands of three supergiant elliptical galaxies: NGC 4874 and NGC 4889 in the Coma cluster, and the radio galaxy NGC 6251. The profiles of NGC 4874 and NGC 4889 are closely fitted by King models. The profile of NGC 6251 cannot be fitted by a King model, nor by a King model plus a central point luminosity source (the presence of which is suggested by a blue trend in the colors at small radii). The previously studied profile of M87, when convolved with an appropriate Gaussian function to allow for the difference in distance, closely resembles the profile of NGC 6251 (but not those of NGC 4874 or NGC 4889). NGC 6251 was successfully fitted with a luminosity profile containing both a point luminosity source and a central point mass. The value of this point mass cannot be determined without additional dynamical data. However, if the core velocity dispersion is similar to that of other giant ellipticals of the same absolute magnitude, the point mass is likely to be about 2.4 x 10^9 M_⊙, similar to the value reported earlier for M87. The data are also used to derive upper limits for possible central point masses in NGC 4874 and NGC 4889

    Neurophysiology

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    Contains reports on four research projects.National Science Foundation (Grant G-16526)National Institutes of Health (Grants MH-04737-03 and NB-04985-01)United States Air Force, Aeronautical Systems Division (Contract AF33(616)-7783)United States Air Force (Contract AF19(604)-6619), administered by Montana State CollegeNational Aeronautics and Space Administration (Grant NsG-496)Teagle Foundation, IncorporatedBell Telephone Laboratories, Incorporate

    Ion Beam Analyses of Carbon Nanotubes

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    Bias in the journal impact factor

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    The ISI journal impact factor (JIF) is based on a sample that may represent half the whole-of-life citations to some journals, but a small fraction (<10%) of the citations accruing to other journals. This disproportionate sampling means that the JIF provides a misleading indication of the true impact of journals, biased in favour of journals that have a rapid rather than a prolonged impact. Many journals exhibit a consistent pattern of citation accrual from year to year, so it may be possible to adjust the JIF to provide a more reliable indication of a journal's impact.Comment: 9 pages, 8 figures; one reference correcte
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