Determinants of albuminuria in all subjects.

<p>Values expressed as odds ratio (OR) and 95% confidence interval (CI).</p><p>Abbreviations are the same as in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0096362#pone-0096362-t001" target="_blank">Table 1</a>.</p

Determinants of MetS in all subjects.

<p>Values expressed as odds ratio (OR) and 95% confidence interval (CI).</p><p>Abbreviations are the same as in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0096362#pone-0096362-t001" target="_blank">Table 1</a>.</p

Comparison of baseline characteristics between relatives of HD patients and community controls.

<p>Abbreviation: HD, hemodialysis; BP, blood pressure; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; eGFR, estimated glomerular filtration rate; MetS, metabolic syndrome; FRS, Framingham Risk Score.</p><p>The FRS is used to identify individuals categorically as “low” (<10% of 10-year risk), or “high” risk (≥10% of 10-year risk).</p

Determinants of MetS, albuminuria, and high FRS risk in relatives of HD patients.

<p>Values expressed as odds ratio (OR) and 95% confidence interval (CI).</p><p>For MetS: adjusted for age, sex, smoking, betel nut chewing, total cholesterol, LDL-C, uric acid, eGFR, and albuminuria.</p><p>For albuminuria: adjusted for age, sex, diabetes mellitus, hypertension, smoking, betel nut chewing, total cholesterol, HDL-C, LDL-C, log-transformed triglycerides, uric acid, eGFR, and MetS.</p><p>For high FRS risk: adjusted for betel nut chewing, diabetes mellitus, log-transformed triglycerides, LDL-C, uric acid, eGFR, albuminuria, and MetS.</p><p>Abbreviations are the same as in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0096362#pone-0096362-t001" target="_blank">Table 1</a>.</p><p>The FRS is used to identify individuals categorically as “low” (<10% of 10-year risk), or “high” risk (≥10% of 10-year risk).</p

Comparison of baseline characteristics among female patients stratified on BMI categories.

<p>Data expressed as mean ± standard deviation, median (interquartile range) or percentage.</p><p>Abbreviations are the same as in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0126668#pone.0126668.t001" target="_blank">Table 1</a>.</p><p>Comparison of baseline characteristics among female patients stratified on BMI categories.</p

The cumulative probability of all-cause mortality using the Kaplan-Meier method in male (A) and female (B) patients according to the categories of body mass index (BMI).

<p>The cumulative probability of all-cause mortality using the Kaplan-Meier method in male (A) and female (B) patients according to the categories of body mass index (BMI).</p

Multivariate-adjusted hazard ratios (HRs) of cardiovascular (CV) events and death according to the categories of body mass index (BMI) in male (■) and female (△) patients.

<p>Error bars indicate 95% confidence intervals. Multivariate-adjusted HRs were adjusted for age, gender, cardiovascular disease, diabetes mellitus, mean arterial pressure, glycated hemoglobin, log-transformed total cholesterol, current smoking status, log-transformed C-reactive protein, estimated glomerular filtration rate, log-transformed urine protein-to-creatinine ratio, albumin, hemoglobin, and phosphorus, using participants with a BMI of 27.6–30.0 kg/m² as the reference group.</p

Multivariate-adjusted hazard ratios (HRs) of all-cause mortality according to the categories of body mass index (BMI) in male (■) and female (△) patients.

<p>Error bars indicate 95% confidence intervals. Multivariate-adjusted HRs were adjusted for age, gender, cardiovascular disease, diabetes mellitus, mean arterial pressure, glycated hemoglobin, log-transformed total cholesterol, current smoking status, log-transformed C-reactive protein, estimated glomerular filtration rate, log-transformed urine protein-to-creatinine ratio, albumin, hemoglobin, and phosphorus, using participants with a BMI of 27.6–30.0 kg/m² as the reference group.</p

The cumulative probability of cardiovascular (CV) events and death using the Kaplan-Meier method in male (A) and female (B) patients according to the categories of body mass index (BMI).

<p>The cumulative probability of cardiovascular (CV) events and death using the Kaplan-Meier method in male (A) and female (B) patients according to the categories of body mass index (BMI).</p

Kaplan-Meier survival curve for commencing dialysis based on fluid overload (relative hydration status, △HS≧7%) and diabetes mellitus (DM).

<p>Kaplan-Meier survival curve for commencing dialysis based on fluid overload (relative hydration status, △HS≧7%) and diabetes mellitus (DM).</p