Van Gogh\u27s Asylum Days

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Le Messager: Lewiston\u27s French language newspaper will be recorded by state for posterity [Article]

Article from an unknown source by Jennifer Sullivan about the Maine State Library\u27s efforts to preserve Le Messager on microfilm with a federal grant from the National Endowment from the Humanities.https://digitalcommons.usm.maine.edu/le-messager/1052/thumbnail.jp

This Irish Summer

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Campus Update: July/August 1990 v. 2, no. 6

Monthly newsletter of the BU Medical CampusNote: misnumbered v. 3, no.

Laying Out an Unwelcome Mat to Public Beach Access

Florida beaches attract tourists from around the world. However, many are unaware of the issues surrounding public beach access; issues that potentially threaten the ability of the Florida visitor to enjoy the warm sands and blue waters that define the state to many. In her comment, Ms. Sullivan revisits the issue of public beach access and the doctrine of customary usage. Specifically, the battle that is occurring in the over-development of Florida Panhandle beaches is analyzed, with the fishing village of Destin serving as a prime example. The effect of recent Florida decisions concerning strict adherence to local comprehensive plans is applied to the current problems facing Panhandle beaches. Finally, Ms. Sullivan documents four distinct areas that have historically proved problematic within other areas of the state and discusses potential remedies as applied to the village of Destin

Sex-specific computational models of the spontaneously hypertensive rat kidneys: factors affecting nitric oxide bioavailability

Sex-specific computational models of the spontaneously hypertensive rat kidneys: factors affecting nitric oxide bioavailability. Am J Physiol Renal Physiol 313: F174 –F183, 2017. First published March 29, 2017; doi:10.1152/ajprenal.00482.2016.—The goals of this study were to 1) develop a computational model of solute transport and oxygenation in the kidney of the female spontaneously hypertensive rat (SHR), and 2) apply that model to investigate sex differences in nitric oxide (NO) levels in SHR and their effects on medullary oxygenation and oxidative stress. To accomplish these goals, we first measured NO synthase (NOS) 1 and NOS3 protein expression levels in total renal microvessels of male and female SHR. We found that the expression of both NOS1 and NOS3 is higher in the renal vasculature of females compared with males. To predict the implications of that finding on medullary oxygenation and oxidative stress levels, we developed a detailed computational model of the female SHR kidney. The model was based on a published male kidney model and represents solute transport and the biochemical reactions among O2, NO, and superoxide (O2 ) in the renal medulla. Model simulations conducted using both male and female SHR kidney models predicted significant radial gradients in interstitial fluid oxygen tension (PO2) and NO and O2 concentration in the outer medulla and upper inner medulla. The models also predicted that increases in endothelial NO-generating capacity, even when limited to specific vascular segments, may substantially raise medullary NO and PO2 levels. Other potential sex differences in SHR, including O2 production rate, are predicted to significantly impact oxidative stress levels, but effects on NO concentration and PO2 are limited.This research was supported by the National Institute of Diabetes and Digestive and Kidney Diseases Grant R01-DK-106102 to A. T. Layton, and by American Heart Association Grant 14GRNT20480199 to J. C. Sullivan. (R01-DK-106102 - National Institute of Diabetes and Digestive and Kidney Diseases; 14GRNT20480199 - American Heart Association)Accepted manuscrip

Navigating the Financial Aid Process

Whether you\u27re a current college student, current educator, or a community member, this session will help cover the basics of financial aid programs and also discuss TEACH grant programs and federal loan forgiveness programs