Correlations between established telomere length predictors and measured relative telomere length in the study sample.

<p>Pearson correlation coefficients used for all variables except ordinal smoking status.</p><p>^aSpearman correlation coefficient used in calculation.</p><p>Correlations between established telomere length predictors and measured relative telomere length in the study sample.</p

Adjusted* least-squares mean telomere length <i>z</i>-scores, by phobic anxiety level, stratified by paternal age (<40 or ≥40 years).

<p>*, Models were adjusted for age in years (continuous), pack-years of smoking (0, >0 to <20, 20 to <40, ≥40), body mass index (continuous, kg/m²) and physical activity (continuous, MET-hrs/wk). Least squares means and 95% confidence intervals are shown. N = 281 excluded due to missing paternal age. ^‡, P-value for test of difference in least-squares means.</p

Least-squares mean leukocyte telomere length z-scores (standard errors), by phobic anxiety categories.

*<p>Adjusted for age in years (continuous), paternal age-at-birth (15–24, 25–29, 30–34, 35–39, ≥40 years), pack-years of smoking (0, 0< to <20, 20 to <40, 40+), physical activity (continuous, MET-hrs/wk), body mass index (continuous, kg/m²).</p>†<p>Adjusted for model I variables, plus chronic medical conditions/potential intermediates: hypertension (yes/no), dyslipidemia (yes/no), diabetes (yes/no), cardiovascular disease (yes/no).</p

Characteristics by phobic anxiety categories (lowest to highest) at blood draw (n = 5,243)^*.

*<p>Due to rounding, percentages may not sum to 100.0.</p>†<p>Combined alpha-linolenic acid and long-chain omega-3 fatty acids (docosahexaenoic and eicosapentaenoic acids).</p

Adjusted* least-squares mean telomere length <i>z</i>-scores, by phobic anxiety level, stratified by smoking status (never or current/past).

<p>*, Models were adjusted for age in years (continuous), paternal age-at-birth (15–24, 25–29, 30–34, 35–39, ≥40 years), body mass index (continuous, kg/m²) and physical activity (continuous, MET-hrs/wk). Least squares means and 95% confidence intervals are shown. N = 20 excluded due to missing smoking status. ^‡, P-value for test of difference in least-squares means.</p

Least-squares mean leukocyte telomere length z-scores (standard errors), by high phobic anxiety.

*<p>Adjusted for age in years (continuous), paternal age-at-birth (15–24, 25–29, 30–34, 35–39, ≥40 years), pack-years of smoking (0, 0< to <20, 20 to <40, 40+), physical activity (continuous, MET-hrs/wk), body mass index (continuous, kg/m²).</p>†<p>Adjusted for model I variables, plus chronic medical conditions/potential intermediates: hypertension (yes/no), dyslipidemia (yes/no), diabetes (yes/no), cardiovascular disease (yes/no).</p>‡<p>P-value for test of difference in least-squares means.</p

Age and age-adjusted characteristics of 3,968 women in the Nurses' Health Study by telomere length (<i>z</i>-score), 1989–1990.^a,b

<p>Age and age-adjusted characteristics of 3,968 women in the Nurses' Health Study by telomere length (<i>z</i>-score), 1989–1990.^{<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0052240#nt102" target="_blank">a,b</a>}</p

Associations among body mass index, type 2 diabetes, and their respective genetic risk scores, Nurses' Health Study, 1989–1990.

<p>Associations among body mass index, type 2 diabetes, and their respective genetic risk scores, Nurses' Health Study, 1989–1990.</p

Least squares mean telomere length (<i>z</i>-score) and 95% CI by genetic risk scores of common risk variants associated with higher body mass index or type 2 diabetes, Nurses' Health Study, 1989–1990.

<p>Least squares mean telomere length (<i>z</i>-score) and 95% CI by genetic risk scores of common risk variants associated with higher body mass index or type 2 diabetes, Nurses' Health Study, 1989–1990.</p

Selected baseline characteristics of 121,004 eligible women in the California Teachers Study by number of full-term pregnancies at baseline.

<p>Selected baseline characteristics of 121,004 eligible women in the California Teachers Study by number of full-term pregnancies at baseline.</p