Parameters for the distribution of CVD events, their associated risks, and effect size of treatment used in the simulation.

Parameters for the distribution of CVD events, their associated risks, and effect size of treatment used in the simulation.</p

Summary of different simulation scenarios considered.

Summary of different simulation scenarios considered.</p

Flowchart of the microsimulation for hypertension screening scale-up.

CVD, cardiovascular disease; FN, false negative; FP, false positive; LMIC, low- and middle-income country; TN, true negative; TP, true positive.</p

Supporting information.

(DOCX)</p

STRESS checklist.

(DOCX)</p

Fig 4 -

Mean numbers of deaths related to HTN-induced CVD events per year and their 95% credible intervals for the different scenarios for the population of LMICs (S0: Base case, S1: Lower accuracy, S2: Improved accuracy, S3: Increased coverage, S4: Increased coverage and screens completed). CVD, cardiovascular disease; HTN, hypertension; LMIC, low- and middle-income country.</p

Members of the HPACC Consortium.

(DOCX)</p

Characteristics of the simulated population at initiation.

Characteristics of the simulated population at initiation.</p

Fig 2 -

(A) Absolute numbers of new detected persons with HTN and (B) total number of detected persons with HTN for the different scenarios in LMICs; S0: Base case, S1: Lower accuracy, S2: Improved accuracy, S3: Increased coverage, S4: Increased coverage and screens completed. The bold line represents the mean value and the band the 95% credible interval. The years of model adaptation are excluded in the figure. HTN, hypertension; LMIC, low- and middle-income country.</p

Fig 3 -

Mean percentage and 95% credible intervals of the reduction of CVD events attributable to HTN per year of the scenarios S1: Lower accuracy, S2: Improved accuracy, S3: Increased coverage, and S4: Increased coverage and screens completed compared to the baseline case S0. The bold line represents the mean value and the band the 95% credible interval. The first years of model adaptation are excluded in the figure. CVD, cardiovascular disease; HTN, hypertension.</p