Additional file 4: Table S3. of Leveraging global gene expression patterns to predict expression of unmeasured genes

Filtering of samples using inclusion criteria. (XLSX 9 kb

Additional file 2: Figure S1-S6. of Leveraging global gene expression patterns to predict expression of unmeasured genes

Additional figures provided illustrate network structure of GGS selected and predictable genes, parameter sweep results using candidate genesets, imputation accuracy using candidate genesets, and imputation accuracy in RNA-seq data. (PDF 1622 kb

Additional file 1: Table S1. of Leveraging global gene expression patterns to predict expression of unmeasured genes

Distribution of eligible genes across PANTHER Go-slim pathways. (XLSX 22 kb

Additional file 3: Table S2. of Leveraging global gene expression patterns to predict expression of unmeasured genes

Summary of GGS parameter sweep and expression prediction results. (XLSX 46 kb

Six-way Venn diagram showing polymorphic putative functional variants shared by reported ethnicities.

<p>Numbers of shared variants are shown at intersections. The total numbers of polymorphic variants by ethnicity are listed in the upper-left hand corner.</p

Cases and Controls by Reported Ethnicity and Study.

<p>Cases and Controls by Reported Ethnicity and Study.</p

Manhattan plots for the endometrial cancer association analysis.

<p>Results of single variant analyses (−log₁₀p) are plotted against chromosome position (NCBI build 37) for association over all ethnicities (A) and for associations within Caucasians (B). Suggestive variants are labeled above. Results were adjusted for age at diagnosis, BMI, study site, plate, and the first four principal components.</p

Top five most significant associations of single coding variants with endometrial cancer risk.^*

<p>*Adjusted for age at diagnosis, BMI at diagnosis, study site, plate, and the first four principal components.</p

Six-way Venn diagram showing polymorphic putative functional variants shared by reported ethnicities.

<p>Numbers of shared variants are shown at intersections. The total numbers of polymorphic variants by ethnicity are listed in the upper-left hand corner.</p

Minor allele frequency for all variants successfully genotyped over all ethnicities.

<p>The number of variants is plotted by the minor allele frequency over all ethnicities. These variants include those that are monomorphic in all ethnicities.</p