Age-adjusted seroprevalence in community and school surveys (all children) by transmission intensity.

<p>The age-adjusted community seroconversion curves (solid) and school aged population (dashed lines). The different transmission intensities are represented as: high (red) moderate (green) and low (blue).</p

Prevalence of malaria infection: adjusted school vs. community surveys in 46 clusters by RDT and serology.

<p>Scatter plots are shown with the line of perfect concordance (x=y) and the data’s reduced major axis using total least squares regression. (A) RDT prevalence per cluster in community vs. adjusted prevalence in all school children. (B) RDT prevalence per cluster in community vs. adjusted school prevalence restricting to children residing within 600m from school.</p

Characteristics of the study population – age and distance travelled to school.

<p>(A) A population pyramid showing the age distribution of those sampled in the community survey compared to those sampled during the school survey. (B) Histogram depicting the distance between the school and compound where each child resides. (C) The proportion of children sampled at each school that reside within 600m of the school.</p

Prevalence of malaria infection in school vs. community surveys in 46 clusters by RDT and serology.

<p>Scatter plots are shown with the line of perfect concordance (x=y) and the data’s reduced major axis using total least squares regression. (A) RDT prevalence per cluster in community vs. all school children. (B) RDT prevalence per cluster in community vs. school children residing within 600m from school. (C) Seroprevalence per cluster in community vs. all school children. (D) Seroprevalence per cluster in community vs. school children residing within 600m from school.</p

Spatial distribution of school study participants, location of the schools, and community catchment area.

<p>Each point represents the compound of a child included in the study. The black crosses indicate the location of each school that was included in the survey. The black circular outline corresponds to the area with a 600m radius around each school and thus represents the community catchment area sampled during the community survey.</p

Dataset 1. Information on the 276 SNPs genotyped in 177 genes in P. falciparum parasite populations from The Gambia, Kilifi and Rachuonyo South

<p><b>Dataset 1:</b> <b>Information on the 276 SNPs genotyped in 177 genes in <i>P. falciparum </i>parasite populations from The Gambia, Kilifi and Rachuonyo South. </b>The columns contain the following information: study_location, site of sample collection; sample_id, unique sample identifier; gene_symbol, gene name (if available); chr_valid, chromosome; coord_valid= base position of SNP on chromosome; sequence_code, SNP name; assay_code, name of assay; rsnumber, unique SNP identifier in dbSNP; reference_allele, 3D7 reference allele, alternative_allele, alternative allele; single letter code, IUPAC code for SNPs; result, genotype call after processing; allele1, IUPAC code for allele 1; allele2, IUPAC code for allele 2; allele_ratio1, proportion of allele 1; allele_ratio2, proportion of allele 2; pass_fail, coding of SNP based on availability of valid genotype (pass) or lack of a valid genotype (fail). Geospatial data for homestead location is considered sensitive data and therefore cannot be made open access. However, it can be accessed through a request to our data governance committee, using the email address mmunene@uat/newsite. </p

Dataset 1: Information on the 276 SNPs genotyped in 177 genes in P. falciparum parasite populations from The Gambia, Kilifi and Rachuonyo South

<p><b>Dataset 1:</b> <b>Information on the 276 SNPs genotyped in 177 genes in <i>P. falciparum </i>parasite populations from The Gambia, Kilifi and Rachuonyo South. </b>The columns contain the following information: study_location, site of sample collection; sample_id, unique sample identifier; gene_symbol, gene name (if available); chr_valid, chromosome; coord_valid= base position of SNP on chromosome; sequence_code, SNP name; assay_code, name of assay; rsnumber, unique SNP identifier in dbSNP; reference_allele, 3D7 reference allele, alternative_allele, alternative allele; single letter code, IUPAC code for SNPs; result, genotype call after processing; allele1, IUPAC code for allele 1; allele2, IUPAC code for allele 2; allele_ratio1, proportion of allele 1; allele_ratio2, proportion of allele 2; pass_fail, coding of SNP based on availability of valid genotype (pass) or lack of a valid genotype (fail). Geospatial data for homestead location is considered sensitive data and therefore cannot be made open access. However, it can be accessed through a request to our data governance committee, using the email address mmunene@uat/newsite. </p