Critical appraisal of included studies.

<p>Critical appraisal of included studies.</p

Clinical signs assessment and blood loss estimation method.

<p>VEBL – Visual estimation of blood loss; LBNP – Low body negative pressure.</p

Characteristics of included studies.

<p>VEBL – Visual estimation of blood loss; LBNP – Low body negative pressure.</p

Clinical signs associated to mortality in included studies.

<p>Clinical signs associated to mortality in included studies.</p

Clinical signs statistical analysis.

<p>AUC –Area under curve; HR - Heart Rate; SBP - Systolic Bood Pressure; SI - Shock Index; PSBP - Prehospital Systolic Blood Pressure; MAP - Mean Arterial Pressure; DPBP - Diastolic Blood Pressure; PP - pulse pressure; BT - Body Temperature; RR - respiratory rate; *BP – no specification if systolic or diastolic.</p

Flow diagram of identification and retrieval of examined studies.

<p>Flow diagram of identification and retrieval of examined studies.</p

Inclusion and exclusion criteria.

<p>Inclusion and exclusion criteria.</p

Association between blood loss and changes in vital signs.

<p>BLE - Blood loss estimation; HR - Heart Rate; SBP - Systolic Bood Pressure; SI - Shock Index; PSBP - Prehospital Systolic Blood Pressure; MAP - Mean Arterial Pressure; DBP - Diastolic Blood Pressure; PP - pulse pressure; BT - Body Temperature; RR - respiratory rate;</p><p>•there is an association between blood loss and changes in the vital sign; ○: there is no association between blood loss and changes in the vital sign;</p>*<p>•: no specification if systolic or diastolic.</p