Characteristics of Thiamin and Its Relevance to the Management of Heart Failure

Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/141593/1/ncp0487.pd

Metabolic and Nutritional Aspects of Acute Renal Failure in Critically Ill Patients Requiring Continuous Renal Replacement Therapy

Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/141368/1/ncp0176.pd

Forest gene diversity is correlated with the composition and function of soil microbial communities

The growing field of community and ecosystem genetics indicates that plant genotype and genotypic variation are important for structuring communities and ecosystem processes. Little is known, however, regarding the effects of stand gene diversity on soil communities and processes under field conditions. Utilizing natural genetic variation occurring in Populus spp. hybrid zones, we tested the hypothesis that stand gene diversity structures soil microbial communities and influences soil nutrient pools. We found significant unimodal patterns relating gene diversity to soil microbial community composition, microbial exoenzyme activity of a carbon‐acquiring enzyme, and availability of soil nitrogen. Multivariate analyses indicate that this pattern is due to the correlation between gene diversity, plant secondary chemistry, and the composition of the microbial community that impacts the availability of soil nitrogen. Together, these data from a natural system indicate that stand gene diversity may affect soil microbial communities and soil processes in ways similar to species diversity (i.e., unimodal patterns). Our results further demonstrate that the effects of plant genetic diversity on other organisms may be mediated by plant functional trait variation.Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/147191/1/pope0035.pd

American Society for Parenteral and Enteral Nutrition and Academy of Nutrition and Dietetics

Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/141469/1/ncp0792.pd

Amphiphilic Cross-Linked Liquid Crystalline Fluoropolymer-Poly(ethylene glycol) Coatings for Application in Challenging Conditions: Comparative Study between Different Liquid Crystalline Comonomers and Polymer Architectures

Linear and hyperbranched poly­(ethylene glycol)-cross-linked amphiphilic fluoropolymer networks comprised of different liquid crystalline comonomers were developed and evaluated as functional coatings in extreme weather-challenging conditions. Through variation of the liquid-crystalline comonomer and hydrophilic:hydrophobic component ratios, several series of coatings were synthesized and underwent a variety of analyses including differential scanning calorimetry, water contact angle measurements and solution stability studies in aqueous media. These materials maintained an unprecedented reduction in the free water melting transition (<i>T</i>_m) temperature across the hyperbranched and linear versions. The coatings synthesized from hyperbranched fluoropolymers preserved the liquid crystalline character of the mesogenic components, as seen by polarized optical microscopy, and demonstrated stability in saltwater aqueous environments and in cold weather conditions

Synthetic Polymer Nanoparticles Conjugated with FimH_A from E. coli Pili to Emulate the Bacterial Mode of Epithelial Internalization

Amphiphilic block copolymer nanoparticles are conjugated with uropathogenic Escherichia coli type 1 pilus adhesin FimH_A through amidation chemistry to enable bladder epithelial cell binding and internalization of the nanoparticles in vitro