The prevalence of left ventricular (LV) diastolic dysfunction in PD patients divided into tertiles based on interleukin-6 (IL-6) and tumor necrosis factor-α (TNF-α) levels.

<p>The prevalence of left ventricular (LV) diastolic dysfunction in PD patients divided into tertiles based on interleukin-6 (IL-6) and tumor necrosis factor-α (TNF-α) levels.</p

Multivariable logistic regression models for parameters associated with left ventricular diastolic dysfunction.

<p>Models 2–4 adjust for age, gender, BMI, DM, HTN, HOMA, and LDL. Models 5 and 6 additionally adjust for tissue necrosis factor-alpha.</p><p>Abbreviations: BMI, body mass index; DM, diabetes mellitus; HTN, hypertension; HOMA, homeostasis model of insulin resistance; TNF-α, tissue necrosis factor-alpha; LDL, low-density lipoprotein; LV, left ventricular.</p

Baseline patient demographics, echocardiographic characteristics, and adipose tissue measurements of the 173 subjects included in the study.

<p>Data are presented as mean ± standard deviation unless otherwise indicated.</p><p>Abbreviations: BMI, body mass index; WC, waist circumflex; DM, diabetes; HTN, hypertension; HOMA, homeostasis model of insulin resistance; TNF-α, tissue necrosis factor-alpha; IL-6, interleukin-6; LDL, low density lipoprotein; HDL, high density lipoprotein; TG, triglyceride; PD, peritoneal dialysis; kt/v, k- dialyzer clearance of urea, t-dialysis time, v-volume of distribution of urea, approximately equal to patient's total body water; LA, left atrial diameter; LV, left ventricular; E, mitral inflow E wave; A, mitral inflow A wave; DT, mitral inflow deceleration time; Em, Peak annular early diastolic velocity of the lateral mitral annulus in tissue Doppler imaging; IVRT, interventricular relaxation time.</p

Pearson bivariate correlations between adipose tissue and various clinical characteristics.

<p>Abbreviations: BMI, body mass index; HOMA, homeostasis model of insulin resistance; TC, total cholesterol; LDL, low-density lipoprotein; HDL, high-density lipoprotein; LA, left atrial/atrium; LV, left ventricular; E, mitral inflow E wave; A, mitral inflow A wave; Em, Peak annular early diastolic velocity of the lateral mitral annulus in tissue Doppler imaging.</p

Multivariate subdistribution hazard model by using clinical factors and DFAα1 as predictor for cardiac mortality and total mortality.

<p>Multivariate subdistribution hazard model by using clinical factors and DFAα1 as predictor for cardiac mortality and total mortality.</p

Basic characteristics of the study subjects in mortality and survival groups.

<p>Basic characteristics of the study subjects in mortality and survival groups.</p

Univariate subdistribution hazard model by using clinical factors and DFAα1 as predictor for cardiac mortality and total mortality.

<p>Univariate subdistribution hazard model by using clinical factors and DFAα1 as predictor for cardiac mortality and total mortality.</p

The designed patient flow diagram.

<p>The designed patient flow diagram.</p

Correlation between interleukin-6 (IL-6), tissue necrosis factor-alpha (TNF-α), and echocardiographic diastolic function parameters in PD patients.

<p>(A) TNF-α and mitral valve ejection flow deceleration time (DT, r = 0.58, P<0.001); (B) TNF-α and the ratio of mitral valve ejection flow (E) divided by mitral valve atrium flow (A, r = −0.38, P<0.001); (C) TNF-α and the ratio of E divided by early diastolic lengthening velocities in tissue Doppler imaging (Em, r = 0.62, P<0.001); (D) IL-6 and DT (r = 0.71, P<0.001); (E) IL-6 and E/A (r = −0.49, P<0.001); and (F) IL-6 and E/Em (r = 0.62, P<0.001).</p