1,904 research outputs found
Social Status and Optimal Income Taxation
This paper examines the optimal (first-best) fiscal policy in a stochastic, infinite-horizon representative agent model that exhibits consumption-enhanced as well as wealth-enhanced social status in the household utility. We show that the optimal labor tax rate is a positive constant that is used to correct negative consumption externalities. The optimal capital tax rate is also positive in order to overturn agents' status-seeking capital over-accumulation. Moreover, we find that in contrast to a conventional automatic stabilizer, the optimal capital tax moves in the opposite direction with shocks to firms' production technology. This result turns out to be qualitatively consistent with the discernible empirical evidence that many countries have implemented procyclical fiscal policies.Social Status, Optimal Income Taxation
The molecular dipole model and the internal optic modes of the sulfate ion in different crystalline systems.
Extension of strongly nonlinear quasivariational inequalities
AbstractIn this paper, we consider an extension of strongly nonlinear quasivariational inequalities studied by Siddiqi and Ansari. This extended problem also contains several known problems such as quasivariational inequalities and the classical variational inequalities as special cases. We employ the projection method to formulate this extended problem equivalently as a fixed point problem. Some existence results are then derived, and some algorithms for finding approximate solutions are also discussed
Parental CoâConstruction of 5â to 13âYearâOlds\u27 Global SelfâEsteem Through Reminiscing About Past Events
The current study explored parental processes associated with children\u27s global selfâesteem development. Eighty 5â to 13âyearâolds and one of their parents provided qualitative and quantitative data through questionnaires, openâended questions, and a laboratoryâbased reminiscing task. Parents who included more explanations of emotions when writing about the lowest points in their lives were more likely to discuss explanations of emotions experienced in negative past events with their child, which was associated with child attachment security. Attachment was associated with concurrent selfâesteem, which predicted relative increases in selfâesteem 16 months later, on average. Finally, parent support also predicted residual increases in selfâesteem. Findings extend prior research by including younger ages and uncovering a process by which two theoretically relevant parenting behaviors impact selfâesteem development
Fucosyltransferase 1 and 2 play pivotal roles in breast cancer cells.
FUT1 and FUT2 encode alpha 1, 2-fucosyltransferases which catalyze the addition of alpha 1, 2-linked fucose to glycans. Glycan products of FUT1 and FUT2, such as Globo H and Lewis Y, are highly expressed on malignant tissues, including breast cancer. Herein, we investigated the roles of FUT1 and FUT2 in breast cancer. Silencing of FUT1 or FUT2 by shRNAs inhibited cell proliferation in vitro and tumorigenicity in mice. This was associated with diminished properties of cancer stem cell (CSC), including mammosphere formation and CSC marker both in vitro and in xenografts. Silencing of FUT2, but not FUT1, significantly changed the cuboidal morphology to dense clusters of small and round cells with reduced adhesion to polystyrene and extracellular matrix, including laminin, fibronectin and collagen. Silencing of FUT1 or FUT2 suppressed cell migration in wound healing assay, whereas FUT1 and FUT2 overexpression increased cell migration and invasion in vitro and metastasis of breast cancer in vivo. A decrease in mesenchymal like markers such as fibronectin, vimentin, and twist, along with increased epithelial like marker, E-cadherin, was observed upon FUT1/2 knockdown, while the opposite was noted by overexpression of FUT1 or FUT2. As expected, FUT1 or FUT2 knockdown reduced Globo H, whereas FUT1 or FUT2 overexpression showed contrary effects. Exogenous addition of Globo H-ceramide reversed the suppression of cell migration by FUT1 knockdown but not the inhibition of cell adhesion by FUT2 silencing, suggesting that at least part of the effects of FUT1/2 knockdown were mediated by Globo H. Our results imply that FUT1 and FUT2 play important roles in regulating growth, adhesion, migration and CSC properties of breast cancer, and may serve as therapeutic targets for breast cancer
An Improved Low Complexity Algorithm for 2-D Integer Lifting-Based Discrete Wavelet Transform Using Symmetric Mask-Based Scheme
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