99 research outputs found
Holes in the t-J_z model: a thorough study
The t-J_z model is the strongly anisotropic limit of the t-J model which
captures some general properties of the doped antiferromagnets (AF). The
absence of spin fluctuations simplifies the analytical treatment of hole motion
in an AF background and allows us to calculate the single- and two-hole spectra
with high accuracy using regular diagram technique combined with real-space
approach. At the same time, numerical studies of this model via exact
diagonalization (ED) on small clusters show negligible finite size effects for
a number of quantities, thus allowing a direct comparison between analytical
and numerical results. Both approaches demonstrate that the holes have tendency
to pair in the p- and d-wave channels at realistic values of t/J. The
interactions leading to pairing and effects selecting p and d waves are
thoroughly investigated. The role of transverse spin fluctuations is considered
using perturbation theory. Based on the results of the present study, we
discuss the pairing problem in the realistic t-J-like model. Possible
implications for preformed pairs formation and phase separation are drawn.Comment: 21 pages, 15 figure
Ăpoca e Densidade de Semeadura de Aveia Preta (Avena strigosa Schreb.) e AzevĂ©m (Lolium multiflorum Lam.) no Alto Vale do ItajaĂ, Santa Catarina
Aspectos microestruturais da falha de um aço IF deformado via compressĂŁo dinĂąmica a -196ÂșC
EficiĂȘncia fotossintĂ©tica e crescimento de genĂłtipos de abacaxizeiro cultivados in vitro em diferentes qualidades de luz, tipos de frasco de cultivo e concentraçÔes de sacarose
ESTERILIZAĂĂO QUĂMICA E AGENTES GELEIFICANTES ALTERNATIVOS NA PROPAGAĂĂO VEGETATIVA IN VITRO DO ABACAXIZEIRO âVITĂRIAâ
Size Doesn't Matter: Towards a More Inclusive Philosophy of Biology
notes: As the primary author, OâMalley drafted the paper, and gathered and analysed data (scientific papers and talks). Conceptual analysis was conducted by both authors.publication-status: Publishedtypes: ArticlePhilosophers of biology, along with everyone else, generally perceive life to fall into two broad categories, the microbes and macrobes, and then pay most of their attention to the latter. âMacrobeâ is the word we propose for larger life forms, and we use it as part of an argument for microbial equality. We suggest that taking more notice of microbes â the dominant life form on the planet, both now and throughout evolutionary history â will transform some of the philosophy of biologyâs standard ideas on ontology, evolution, taxonomy and biodiversity. We set out a number of recent developments in microbiology â including biofilm formation, chemotaxis, quorum sensing and gene transfer â that highlight microbial capacities for cooperation and communication and break down conventional thinking that microbes are solely or primarily single-celled organisms. These insights also bring new perspectives to the levels of selection debate, as well as to discussions of the evolution and nature of multicellularity, and to neo-Darwinian understandings of evolutionary mechanisms. We show how these revisions lead to further complications for microbial classification and the philosophies of systematics and biodiversity. Incorporating microbial insights into the philosophy of biology will challenge many of its assumptions, but also give greater scope and depth to its investigations
APOL1 genotype-associated morphologic changes among patients with focal segmental glomerulosclerosis
Background: The G1 and G2 alleles of apolipoprotein L1 (APOL1) are common in the Black population and associated with increased risk of focal segmental glomerulosclerosis (FSGS). The molecular mechanisms linking APOL1 risk variants with FSGS are not clearly understood, and APOL1âs natural absence in laboratory animals makes studying its pathobiology challenging. Methods: In a cohort of 90 Black patients with either FSGS or minimal change disease (MCD) enrolled in the Nephrotic Syndrome Study Network (58% pediatric onset), we used kidney biopsy traits as an intermediate outcome to help illuminate tissue-based consequences of APOL1 risk variants and expression. We tested associations between APOL1 risk alleles or glomerular APOL1 mRNA expression and 83 light- or electron-microscopy traits measuring structural and cellular kidney changes. Results: Under both recessive and dominant models in the FSGS patient subgroup (61%), APOL1 risk variants were significantly correlated (defined as FDR <0.1) with decreased global mesangial hypercellularity, decreased condensation of cytoskeleton, and increased tubular microcysts. No significant correlations were detected in MCD cohort. Independent of risk alleles, glomerular APOL1 expression in FSGS patients was not correlated with morphologic features. Conclusions: While APOL1-associated FSGS is associated with two risk alleles, both one and two risk alleles are associated with cellular/tissue changes in this study of FSGS patients. Our lack of discovery of a large group of tissue differences in FSGS and no significant difference in MCD may be due to the lack of power but also supports investigating whether machine learning methods may more sensitively detect APOL1-associated changes
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