I.C.E.: a Transportable Atomic Inertial Sensor for Test in Microgravity

We present our the construction of an atom interferometer for inertial sensing in microgravity, as part of the I.C.E. (\textit{Interf\'{e}rom\'{e}trie Coh\'{e}rente pour l'Espace}) collaboration. On-board laser systems have been developed based on fibre-optic components, which are insensitive to mechanical vibrations and acoustic noise, have sub-MHz linewidth, and remain frequency stabilised for weeks at a time. A compact, transportable vacuum system has been built, and used for laser cooling and magneto-optical trapping. We will use a mixture of quantum degenerate gases, bosonic $^{87}$Rb and fermionic $^{40}$K, in order to find the optimal conditions for precision and sensitivity of inertial measurements. Microgravity will be realised in parabolic flights lasting up to 20s in an Airbus. We show that the factors limiting the sensitivity of a long-interrogation-time atomic inertial sensor are the phase noise in reference frequency generation for Raman-pulse atomic beam-splitters and acceleration fluctuations during free fall

A simplified table using validated diagnostic criteria is effective to improve characterization of colorectal polyps: the CONECCT teaching program

International audienceIntroduction and study aims Accurate real-time endoscopic characterization of colorectal polyps is key to choosing the most appropriate treatment. Mastering the currently available classifications is challenging. We used validated criteria for these classifications to create a single table, named CONECCT, and evaluated the impact of a teaching program based on this tool.Methods A prospective multicenter study involving GI fellows and attending physicians was conducted. During the first session, each trainee completed a pretest consisting in histological prediction and choice of treatment of 20 colorectal polyps still frames. This was followed by a 30-minute course on the CONECCT table, before taking a post-test using the same still frames reshuffled. During a second session at 3 – 6 months, a last test (T3 M) was performed, including these same still frames and 20 new ones.Results A total 419 participants followed the teaching program between April 2017 and April 2018. The mean proportion of correctly predicted/treated lesions improved significantly from pretest to post-test and to T3 M, from 51.0 % to 74.0 % and to 66.6 % respectively (P < 0.001). Between pretest and post-test, 343 (86.6 %) trainees improved, and 153 (75.4 %) at T3 M. Significant improvement occurred for each subtype of polyp for fellows and attending physicians. Between the two sessions, trainees continued to progress in the histology prediction and treatment choice of polyps CONECCT IIA. Over-treatment decreased significantly from 30.1 % to 15.5 % at post-test and to 18.5 % at T3 M (P < 0.001).Conclusion The CONECCT teaching program is effective to improve the histology prediction and the treatment choice by gastroenterologists, for each subtype of colorectal polyp

Les impacts de l'autoconsommation d'électricité photovoltaïque sur les coûts de développement et d'exploitation du réseau

DauphineL’autoconsommation d’électricité consiste à produire une partie de l’électricité que l’on consomme. Elle implique des économies de facture pour les consommateurs ainsi -cettes des gestionnaires de réseaux. Un développement massif de l’autoconsommation pourrait compromettre le financement des infrastructures de transport et de distribution d’électricité et remettre en cause le système actuel de tarification de l’accès au réseau

Calibration of Visual Sensors and Actuators in Distributed Computing Platforms

Many novel multimedia applications such as virtual immersive environments use multiple sensors and actuators. We present in this paper a novel approach for position calibration of visual sensors and actuators, i.e. cameras and displays, in a distributed network of general purpose computing devices. The proposed approach is very suitable for the calibration of mobile setups since (a) synchronization of the setup is not required, (b) it works fully automatic, (c) only weak restrictions are imposed on the positioning of the cameras and displays, and (d) no upper limit on the number of cameras and displays to calibrated is imposed. Corresponding points across different camera images are established automatically and found with subpixel accuracy. Cameras do not have to share one common view, only a reasonable overlap between camera subgroups is necessary. The method has been sucessfully tested in numerous multicamera environments with a varying number of cameras. It has proven itself to work extremely accurate. Performance results are reported

Bevacizumab et atteinte digestive de la maladie de Rendu Osler (impact clinique, biologique et endoscopique, étude de 10 cas)

LYON1-BU Santé (693882101) / SudocSudocFranceF

Precise Visibility Determination of Displays in Camera Images

In many novel application scenarios such as smart rooms or sensing rooms visual sensors (such as cameras) need to know which visual actuators (such as displays) are visible to them. Often only parts of a display are visible from a camera. Therefore, a novel algorithm for precise visibility determination is presented. The algorithm makes the assumption that the displays are active, i.e., they can be controlled by the application. Under these conditions the algorithm determines precisely where which parts of a display are imaged by a camera

Analyse et exploitation de données de criblages de réactions chimiques pour la recherche de voies de synthèse

Les bases de données en chimie sont généralement centrées sur les molécules et les informations concernant les réactions sont extraites des publications scientifiques. Ces informations sont généralement disponibles dans des conditions expérimentales particulières et peu de données sont disponibles au sujet des réactions à faible rendement ou qui n ont pas fonctionnées. En conséquence il peut être difficile de comparer les réactions et les transformations chimiques entre elles en raison de ces conditions expérimentales spécifiques et de ces données manquantes. Cette thèse a été financée par la société NovAlix (CIFRE), spécialisée en chimie organique et en biologie structurale. Afin d explorer rapidement l espace chimique et d améliorer le processus de synthèse de molécules, deux méthodes d expérimentation à haut débit ont été mises au point au sein de la société. Ces méthodes s appuient sur la chromatographie en phase gazeuse et sur la spectrométrie de masse pour l analyse des milieux réactionnels. La plate-forme informatique Magellan développée au cours de cette thèse est mise en œuvre grâce aux technologies Java Enterprise Edition et s appuie sur une base de donnée centrée autour de la réaction chimique. Cet application permet la lecture, l analyse et le stockage des données expérimentales récoltées par les méthodes d expérimentation à haut débit de NovAlix et fournit des outils informatiques facilitant l analyse des spectres expérimentaux et permettant la formulation de requêtes sur les expériences ainsi enregistrées.Chemistry databases are centered on chemicals and their reaction data is extracted from scientific literature. They are usually given in non-standardized conditions and in general nothing is available about reactions that did not occur or exhibit a low yield. Thus, it can be difficult to compare reactions and chemical transformations because of the specific experimental conditions and the missing data. This thesis has been funded by NovAlix (CIFRE), a company specialized in organic chemistry synthesis and structural biology. In order to explore the chemical space and improve the chemical synthesis process, two high-throughput reactions screening methods using gas chromatography and mass spectrometry have been set up in NovAlix. The Magellan information system developed during this thesis use a chemical reaction-centric database and is built on Java Enterprise Edition open-source technologies. It allows collecting high-throughput data from mass spectrometry and gas chromatography experimentations realized in standardized conditions. Then, the Magellan application enables the chemist to read and store experimental results, provides tools to help data analysis and query the collected data via a rich-client user interface.STRASBOURG-Sc. et Techniques (674822102) / SudocSudocFranceF