FAKTOR-FAKTOR YANG MEMPENGARUHI KINERJA SISTEM INFORMASI AKUNTANSI PADA PT. GASEKA SURABAYA

PT GASEKA merupakan perusahaan dagang yang bergerak di bidang teknik dan bangunan dengan jumlah jenis barang teknik dan bangunan + 150.000 jenis yang diantaranya adalah semen, besi beton, cat, baut, paku, mur, alat pemotong grenda, batu resibon dan alat-alat teknik serta bangunan lainnya. Akan tetapi, dikarenakan PT. GASEKA mempunyai banyak data barang dagangan sehingga memerlukan pengaturan terhadap jenis barang yang ada dan stok barang yang ada pada gudangnya, maka memerlukan suatu system pencatatan yang dapat memudahkan pengecekan barang dagang yang ada di gudang GASEKA. Hal ini mendorong PT. GASEKA untuk membuat sistem informasi akuntansi online yang dapat memberikan kemudahan dalam pencatatan pemesanan, pengolahan data stok bahan dan pembuatan laporan laba rugi sehingga dapat meminimalkan kesalahan yang dapat terjadi. Pada pembangunan sistem informasi akuntansi online ini penulis mengamati system informasi akuntansi yang ada pada PT. GASEKA apakah sudah sejalan dengan kebutuhan perusahaan. Sehingga user tidak perlu lagi melakukannya dengan cara manual yang dapat menimbulkan kesalahan pencatatan dalam penulisannya, karena hal tersebut sudah dapat ditangani melalui sistem informasi akuntansi

Screening for thyroid disorders in pregnancy with TSH estimation

Background: Thyroid dysfunction is the second common endocrine disorder seen in pregnancy. There are various physiological changes in pregnancy which lead to alterations in thyroxin levels. Hypothyroidism and hyperthyroidism can have effect on pregnancy and fetus. In India there are no guidelines for screening for thyroid disorders in pregnancy. This study was performed to detect thyroid disorders in asymptomatic pregnant women, to treat them early and compare the outcome with normal pregnancies. To evaluate TSH estimation as screening test.Methods: It was a prospective study done at Kempegowda Institute of Medical Sciences Bangalore. 400 asymptomatic pregnant women with singleton pregnancy irrespective of age, gestational age, parity and socioeconomic status were included. Multiple pregnancy and those on treatment for thyroid disorder were excluded. Written informed consent obtained. At first visit detailed history and examination was done .Apart from routine investigations estimation of TSH was done. When the TSH levels were abnormal FT4 and anti TPO antibody was estimated.Results: The incidence of thyroid dysfunction was 12%. The association of risk factors was higher in the screen positive patients which was 28(58.3%) as compared to 44(12.5%) in Euthyroid patients, P <0.001. Maternal complications were more (65.2%) & Premature births 26.1% in patients with thyroid disorders compared to normal women (25.6%) and Premature births 6.92% , P = 0.009 .Conclusions: Screening all pregnant women with TSH for thyroid dysfunction especially those with previous adverse pregnancy outcome is useful. Early diagnosis and treatment will definitely improve the pregnancy outcome

A Maximum Entropy Approach to Defining Cell State

The past few decades have seen great leaps in technologies to analyze cells and tissues. Omics methods in particular now allow us unprecedented access to their the molecular composition where the base-level resolution of transcripts and their numbers can be determined at a single cell level. Existing methods to analyze the resulting data make use of the count data while discarding the information present in the sequences themselves. In this paper we used a maximum entropy approach to develop a method to analyze RNA-seq data using both the sequence and count information. By mapping sequences to vectors of spins and defining an energy function on them, we were able to identify specific states in a biological process using mean energies and their associated Boltzmann-probabilities. This approach opens up new avenues in the quantitative analysis of -omics data and analysis of biological function

Search of dynamic magnetic resonance images using active shape model

This paper focuses on segmenting dynamic magnetic resonance (MR) images of the human heart stored in a database. Heart MR images are dynamic, as the size and shape of a person?s heart vary in time. Active Shape Model segmentation was used to segment dynamic images of the heart. The input data is a points file of a set of random points. This method is economical since points of all the frames need not be placed in the points file for search. Segmented dynamic images of an organ such as a heart would help physicians to better understand certain medical conditions. The novelty of this approach is that it allows automatic segmentation of thousands of dynamic MR images in the database, visualization of the shape variation and retrieval of similar cases of interest from the image database

Ohvira syndrome with left radial hemimelia: a rare association

Ohvira syndrome is rare complex anomaly consisting of uterus didelphys, unilateral ipsilateral obstructed hemivagina and ipsilateral renal agenesis. It typically presents with dysmenorrhea or pelvic pain shortly after menarche due to collection of secretions in the uterus. Reporting a case of 32 years unmarried nulligravida lady with complaints of pain abdomen since 20 days with history of similar complaints 15 years bac. Patient was on Inj. DMPA 2 years back. On examination upper limb skeletal deformity-left radial hemimelia present with a mass of 14-16 weeks gravid uterus on per abdomen examination. USG (February 2020), was suggestive of uterus didelphys bicollis with collection of 108 cc noted in the right uterine cavity with right kidney agenesis with obscured right ovary. Total abdominal hysterectomy with left salphingo-oopherectomy was done. Specimen features were suggestive of uterus didelphys bicornis bicollis with right uterus hematometra with right cervix blind with right sided blind vagina with features suggestive of Ohvira syndrome

Efficacy of an alginate versus proton pump inhibitor in the symptomatic relief of gastroesophageal reflux symptoms in pregnant women

Background: Gastroesophageal reflux disease (GERD) is frequently seen during pregnancy with prevalence of 80%. Proton pump inhibitors (PPI) are the most effective drugs used in the treatment of reflux symptoms. Alginates are natural polysaccharide polymer which builds a non-systemic barrier against acid and food reflux in the oesophagus. Aims and objectives were to compare the efficacy of alginate versus PPIs in pregnant women, and to determine the time to onset of decrease in the pain intensity of alginate to PPIs. Methods: This is a prospective randomised study conducted in pregnant women with symptoms of heartburn comparing the efficacy of alginates to PPIs in Kempegowda Institute of Medical Sciences. After subjects have signed the consent, two sachets of 10 ml liquid preparation alginate were given to the alginate group while 40 mg intravenous pantoprazole to the PPI group. Results: Among 40 patients studied, 20 were given alginates and 20 were given PPIs. 7 presented in the 1st trimester and 33 in 2nd trimester. Onset of action is faster with alginates when compared to PPIs, it was 30 min to 1 hour in patients taking alginates and 6-12 hours in patients taking PPIs, duration of action was longer for PPIs than alginates, with alginates it’s observed that it attains 24-hour symptom free interval in shorter time when compared to PPIs. Conclusions: ¬Alginates to be used for rapid symptom relief in patients with acute symptoms as an induction agent, PPIs to be used for longer duration of action as maintenance.

Comparative study of efficacy and safety of intravenous ferric carboxymaltose versus iron sucrose in treatment of post-partum anemia

Background: Ferric carboxymaltose has been recently introduced for the treatment of anaemia. The present study was planned to compare the efficacy, tolerability and safety of intravenous ferric carboxymaltose with intravenous iron sucrose in the treatment of iron deficiency anaemia among postpartum women.Methods: A total of 60 postpartum women with haemoglobin levels between 7-10 g/dl were randomized into two groups: 30 in group A (received iron carboxymaltose) and 30 in group B (Received iron sucrose). Haemoglobin and serum ferritin levels were done on day 0 and after 6 weeks.Results: The post treatment haemoglobin levels were found to be 10-10.9 g/dl in 66.7% of women in group A and 63.3% in group B. The mean post treatment haemoglobin levels in group A was 9.97±0.3 g/dl and in group B was 10.9 g/dl (p<0.001). The mean increase in haemoglobin levels post treatment were significantly high in group B (2.1±0.5 gm%) compared to group A (1.3±0.5 gm%). The mean post treatment S. Ferritin levels in group A was 91.2±25.8 and in group B was 126.5±23.2 gm%. The mean increase in S. Ferritin levels post treatment were significantly high in group B (96.9±23.3) compared to group A (62.7±22.6) (p<0.001).Conclusions: Intravenous iron carboxymaltose is more effective and better tolerated in the treatment of iron deficiency anaemia among postpartum women compared to intravenous iron sucrose

Short term effects of antenatal maternal betamethasone administration on CTG

Background: Antenatal administration of corticosteroids to pregnant women has proven to enhance lung maturation, prevent respiratory distress syndrome and provide neuroprotection to the foetus. When betamethasone is given antenatally, it has been observed to transiently reduce fetal movements and fetal heart rate variability; which are often used as indicators of fetal wellbeing. Aim and objectives of the present study was planned to assess the short-term effects of antenatal betamethasone administration on fetal heart rate and its variability by visual interpretation of CTGMethods: A total of 30 women between gestational age of 28 weeks to 36 weeks 6 days with singleton pregnancy requiring maternal betamethasone administration were enrolled and the first CTG was taken. First dose of injection betamethasone 12 mg i.v. was administered and second CTG was taken 6 hours later and both the CTGs were compared.Results: After 1st dose of antenatal betamethasone, 90% of the cases had changes in fetal heart rate on CTG. In 53.3% cases, the baseline fetal heart rate was reduced while in 46.7% there was no change. There was reduced fetal heart rate variability in 56.7% cases while 23.3% cases had increased variability and rest 20% had no observable change. 73.3% study patients delivered and 26.6% study patients continued pregnancy. Among those who delivered, 20% neonates required neonatal ventilator support and 10% required oxygen support. All neonates were eventually discharged.Conclusions: Maternal betamethasone administration can cause changes in fetal heart rate and variability on CTG. Hence, other fetal parameters have to be considered before concluding fetal distress as these changes maybe transient. In our study, though CTG changes were seen in 90% cases, only 20% cases required neonatal ventilator support

A Study to Assess the Effectiveness of Music Therapy in Reducing Occupational Pressure among Nurses Working at Institute of Mental Health, Kilpauk, Chennai-10

Nursing has been identified as an occupation that contains high levels of pressure. It has been found that job pressure brought about hazardous impacts not only on nurses health but also in their abilities to cope with job demands. It impairs seriously for the provision of quality care and the efficiency of health services delivery. Nursing has been identified by the number of studies as a Pressure full occupation. Occupational pressure is a recognized problem in health care workers. Occupational pressure is a common work place, problem experienced by all professionals, irrespective nature of work. Occupational pressure has been cited as a significant health problem. Among the staff nurses, the prevalence of job stress was 78% of the staff nurses are having frequent stress and 22% of the nurses are having neutral stress, none of them having no stress or occasional stress or extreme stress. A Complementary therapy like music therapy is effective for reducing stress among staff nurses. TITLE: “A study to assess the effectiveness of music therapy in reducing occupational pressure among nurses working at Institute of Mental Health, Kilpauk, Chennai-10”. OBJECTIVES: 1. To assess and compare the pre test and post test level of occupational pressure among nurses working at Institute of Mental Health, Kilpauk. 2. To evaluate the effectiveness of music therapy on reducing occupational pressure among nurses working at institute of mental health. 3. To associate the post-test of music therapy among nurses and selected demographic variables. MATERIALS AND METHODS: This study was conducted with 100 samples [nurses] in quantitative approach. Pre experimental one group pre test and post test design, sample selection was done by Non-Probability Purposive Sampling technique method. Occupational pressure was assessed by using Standardized Arbor Job Stress Scale questionnaires. After the pre-test, administration of Music therapy was given to nurses working at Institute of Mental Health, Kilpauk, Chennai -10. After 14 days post test was conducted by using same tool. RESULTS: The findings of the present study revealed that the pre test mean pressure score were 38.58, after administration of music therapy the post test pressure score were 22.55 with mean difference is 16.03 which is statistically significant. Statistical significance was calculated by using student‘s paired "t" test. The significant at p<0.001*** level. CONCLUSION: The present study concluded that, nurses working at Institute of Mental Health have significant reduction in occupational pressure levels after administration of music therapy. Hence, administration of music therapy was found to be effective on reduction of occupational pressure levels among the nurses and can be implemented in all settings to promote physiological as well as psychological health

A retrospective study on various methods used in second trimester MTP at KIMS hospital and research centre, Bangalore

Background: Despite the fact that majority of abortions are performed in the first trimester, 10-15% of abortions have taken place in the second trimester period globally because of delayed diagnosis of fetal anomalies and failure to recognize an undesired pregnancy in the first trimester. This study aims to describe the various methods used in inducing second trimester abortions and to analyse the efficacy and safety profile of these methods.Methods: Retrospective observational study. This study analysed case records of 30 patients who underwent second trimester abortion between the gestations of 12 and 28 weeks. All case records of patients who underwent second trimester abortion between the gestation 12 and 28 weeks from 1st January 2021 to 1st August 2021 at the department of obstetrics and Gynaecology, KIMS hospital and Research Centre, Bangalore was analysed. Dilapan-s (hygroscopic mechanical dilator), Foley’s and mifepristone for cervical ripening followed by varying doses of misoprostol are the different methods studied in this study population.Results: Most of the patients in study population belonged to the age group of 28-32 years. 60% patients underwent MTP between the gestational ages of 16-20weeks.The commonest indication for MTP was fetal anomaly.Conclusions: Mifepristone group had short induction to abortion interval but was associated with higher rates of retained placenta bits. Foleys group had the longest induction to abortion interval but reported no complications