Socio-demographic characteristics of the patient cohort (n = 103).

Socio-demographic characteristics of the patient cohort (n = 103).</p

Box and whisker plots illustrating the changes in the disease activity in the patient cohort as assessed by CDAI (a) and DAS 28 (b).

The median disease activities at different time points were compared by the Kruskal-Wallis test (with Dunn’s post-hoc analysis). The drops in the median disease activity down the timeline were statistically significant (p < 0.05). Asterix indicate that the difference between groups is statistically significant. DAS 28 –disease activity score 28, CDAI- clinical disease activity index, 0, 4, and 9 in the x-axis indicate the time point of evaluation (0 –baseline, 4–4 months, and 9–9 months).</p

Scatter plot illustrating linear positive correlation between DAS 28 and CDAI assessed at 3 time points (0 = 0 months, 4 = 4 months, 9 = 9 months).

At all three time points of evaluation, CDAI was strongly correlated with DAS 28; ρ = 0.9357 at 0 months (p<0.05), ρ = 0.9354 at 4 months (p<0.05), ρ = 0.9106 at 9 months (p<0.05). CDAI–clinical disease activity, DAS 28- disease activity score 28.</p

Inter-rater agreement between CDAI and DAS 28 at 3-time points of disease activity assessment.

Inter-rater agreement between CDAI and DAS 28 at 3-time points of disease activity assessment.</p

Raw data.

(XLSX)</p

CDAI cut-off values derived from different studies.

CDAI cut-off values derived from different studies.</p

ROC curve illustrating the sensitivity and 1-specificity for different values of CDAI corresponding to a DAS28 cut off value of 3.2, based on the disease activity evaluation at 4 months.

(TIF)</p

ROC curves.

A. ROC curve illustrating the sensitivity and 1-specificity for different values of CDAI corresponding to a DAS28 cut off value of 5.1, based on the disease activity evaluation at the first visit (0 months). Circles on the ROC curve corresponds to different criterion values of CDAI, B. ROC curve illustrating the sensitivity and 1-specificity for different values of CDAI corresponding to a DAS28 >2.6, based on the disease activity evaluation at 9 months. Optimum CDAI cut-off point were decided based on the Youden’s J statistic. Circles on the ROC curve corresponds to different criterion values of CDAI. CDAI–clinical disease activity, DAS 28- disease activity score 28.</p

Disease characteristics of RA patient at their initial presentation.

Disease characteristics of RA patient at their initial presentation.</p