4 research outputs found
Late breast-milk transmission of NVP-R HIV in seven mother-infant pairs.
<p>NVP-R = nevirapine resistance; WT = wild-type HIV; SWEN = up to six weeks of extended-dose of nevirapine; SD-NVP = single-dose nevirapine; n/a = not applicable.</p>*<p>G190A detected as a mixture with wild-type HIV using standard population sequencing therefore, cloning was not performed in this patient.</p
SWEN and SD-NVP exposed HIV-infected infants diagnosed within the first six weeks of life with NVP-R.
<p>SWEN = up to six weeks of extended-dose nevirapine; SD-NVP = single-dose nevirapine; NVP-R = nevirapine resistance. P-values generated using Fisher's exact test.</p
SWEN and SD-NVP exposed infants infected with HIV after six weeks of age through late-breastfeeding with NVP-R.
<p>SWEN = up to six weeks of extended-dose nevirapine; SD-NVP = single-dose nevirapine; NVP-R = nevirapine resistance. P-values generated using Fisher's exact test.</p
Infant and maternal characteristics by infant intervention.
<p>Data are number of patients (%) unless stated otherwise.</p><p>SWEN = up to six weeks of extended-dose nevirapine; SD-NVP = single-dose nevirapine; AZT = zidovudine; IQR = interquartile range.</p>*<p>All p-values generated using Fisher's exact test for categorical variables and Mann-Whitney test for continuous variables.</p>†<p>Maternal antiretroviral therapy was started after delivery in 11 of 12 women in both groups. Genotypes in 10 of these 11 corresponding infants were obtained prior to initiation of maternal antiretroviral therapy.</p