268 research outputs found

    Cervical cancer vaccine in Pakistan: let\u27s start thinking

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    Monetary-fiscal-trade policy and economic growth in Pakistan: time series empirical investigation

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    This study empirically examines the effect of monetary, fiscal and trade policy on economic growth in Pakistan using annual time series data from 1981 to 2009. Money supply, government expenditure and trade openness are used as proxies of monetary, fiscal and trade policy respectively. Cointegration and error correction model indicate the existence of positive significant long run and short run relationship of monetary and fiscal policy with economic growth. Result also indicates that monetary policy is more effective than fiscal policy in Pakistan. In contrast, trade policy has insignificant effect on economic growth both in the short run and in the long run. In light of the findings, it is suggested that the policy makers should focus more on monetary policy in order to ensure economic growth in the country. It is also recommended that further research should be conducted to find out such components of exports and imports which lead to the ineffectiveness of trade policy to enhance economic growth in Pakistan.Monetary, Fiscal, Trade, Economic Growth

    Comparison of Liquefaction Potential Evaluation Based on Different Field Tests

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    The lowlands of India are vulnerable to possible future large earthquakes. The liquefaction strength is estimated using in-situ tests and the factor of safety against liquefaction by comparing the liquefaction strength with cyclic shear stress ratio developed in the deposit during an earthquake. Standard Penetration test (SPT) and Cone Penetration test(CPT) have been most commonly used in-situ tests for characterization of liquefaction resistance. In this study, liquefaction potential is evaluated based on SPT as well as CPT data obtained from the three different locations situated in alluvial lowlands. A large difference in factor of safety against liquefaction is found based on SPT and CPT data. It is observed that CPT data is more reliable for liquefaction potential evaluation because there is no concrete method available in India to convert measured SPT N-value to (N1)60

    Disease mongering: the role of medical journals

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    Monetary-fiscal-trade policy and economic growth in Pakistan: Time series empirical investigation

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    This study empirically examines the effect of monetary, fiscal and trade policy on economic growth in Pakistan using annual time series data from 1981 to 2009. Money supply, government expenditure and trade openness are used as proxies of monetary, fiscal and trade policy respectively. Cointegration and error correction model indicate the existence of positive significant long run and short run relationship of monetary and fiscal policy with economic growth. Result also indicates that monetary policy is more effective than fiscal policy in Pakistan. In contrast, trade policy has insignificant effect on economic growth both in the short run and in the long run. In light of the findings, it is suggested that the policy makers should focus more on monetary policy in order to ensure economic growth in the country. It is also recommended that further research should be conducted to find out such components of exports and imports which lead to the ineffectiveness of trade policy to enhance economic growth in Pakistan.Monetary, Fiscal, Trade, Economic Growth

    Paediatric mental health in Pakistan: a neglected avenue

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    Inter- and transgenerational inheritance of behavioral phenotypes

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    Adult animal behaviors are determined by complex and dynamic changes in gene expression in different brain regions and are influenced by life experiences and environmental exposures. These stimuli affect gene expression through intricate mechanisms of regulation that largely implicate epigenetic factors, such as, DNA methylation, histone post-translational modifications, and non-coding RNAs (ncRNAs). Through these molecular pathways, some of the behavioral phenotypes associated with life experiences can be stably transmitted to descendants, sometimes across several generations. Rodent studies indicate that parental stressful and traumatic experiences can lead to behavioral despair, risk-taking behaviors, altered sociability and atypical responses to stressful stimuli in the offspring, whereas parental environmental enrichment has been associated with improved cognition and stress resilience in the offspring. Similar observations have been made in humans; children and grandchildren of genocide survivors show increased psychopathology and emotional disturbances. At the molecular level, changes in germline ncRNAs have been identified as likely vectors of transmission in rodents. The mechanisms linking behavioral stimuli to the germline, and factors responsible for these changes and their persistence across generations remain, however, largely unidentified

    Validity of capital asset pricing model: evidence from Karachi stock exchange

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    This study investigates the validity of Capital Asset Pricing (CAP) Model in Karachi stock exchange (KSE). The data of 387 companies of 30 different sectors on monthly, quarterly and semiannual basis are used. The Paired sample t- test is applied to find the difference between actual and expected returns. Results show that capital asset pricing model (CAPM) predict more accurately the expected return on a short term investment as compare to long term investment. It is recommended that the investors should more focus on CAPM results for short term as compare to long term investments in KSE.Portfolio choice, Investment Decisions, Capital Assets Pricing Model, Risk

    Accuracy of computed tomography in differentiating perforated from nonperforated appendicitis, Taking histopathology as the gold standard.

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    Introduction Acute appendicitis is one of the more common causes of acute abdominal pain. It occurs when the lumen of the appendix is obstructed, leading to inflammation and finally perforation. The preoperative differentiation of perforated from nonperforated appendicitis is important and helpful to define prognosis and determine an adequate therapeutic approach, including consideration for nonsurgical treatment. This study recommends computed tomography (CT), a noninvasive method of investigation, be used frequently in clinically suspected cases of perforated appendicitis in the Pakistani population for better patient outcomes. Objective To determine the diagnostic accuracy of CT in differentiating perforated from nonperforated appendicitis by using histopathology as the gold standard. Material and methods A total of 236 patients with a clinical suspicion of appendicitis were included in this study. CT was performed in Liaquat National Hospital and Medical College. At the time of scanning, intravenous contrast was administered. Histopathology was used as the diagnostic gold standard. CT findings were documented using a proforma. The patient was returned to the referring department and followed after surgery for histopathology. Results Sensitivity, specificity, and positive and negative predictive values, as well as the accuracy of CT in the detection of perforated appendicitis, was 71.4%, 90.7%, 62.5%, 93.6%, and 87.3%, respectively. Conclusion CT findings can be used to select patients with perforated appendicitis for initial nonoperative management
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