Study of the protective role of ginseng aqueous extract on Lipid profile (TC), (Tg), (HDL) and (LDL) in male rabbits treated with lead acetate for 30 days

The Study involved twenty healthy adult white male rabbits (Lepus arcticus L.). the average weight (1500- 1600) Kg and aged from eight months to one year. The rabbits ware divided to four groups(G) each group contains five rabbits. G1 was treated with normal saline (1.5) ml orally as negative control group, G2 was treated with lead acetate (150) mg/kg as positive control group, G3 was treated with the aqueous extract of the Panax ginseng  (400 ) mg/kg b.wt  and G4  was  treated with the aqueous extract of the Panax ginseng ( 400) mg/kg b.wt  after 3 hours given them lead acetate (150 mg/kg b. wt/day) for peroid 30 days . study aimed to determine the protective role of Panax ginseng extract on Lipid profile like total cholesterol (TC) , triglycerides (Tg) , high-density lipoproteins (HDL) , low-density lipoproteins(LDL). The result of  present study showed:- increase (P<0.05) in mean levels of high-density lipoproteins (HDL) in the (G3) and (G4) group compare with Second group (positive control G2).  decrease (P<0.05) in mean levels total cholesterol (TC), triglycerides (Tg) low-density lipoproteins(LDL) in group (G3) and (G4) compare with Second group (positive control G2)

Study of the protective role of panax ginseng aqueous extract on the antioxidants glutathione (GSH) and oxidants malondialdehyde (MDA) in male rabbits treated with lead acetate for 30 days

The Study involved twenty healthy adult white male rabbits (Lepus arcticus L.). the average weight (1500- 1600) Kg and aged from eight months to one year. The rabbits ware divided to four groups(G) each group contains five rabbits. G1 was treated with normal saline (1.5) ml orally as negative control group, G2 was treated with lead acetate (150) mg/kg as positive control group, G3 was treated with the aqueous extract of the Panax ginseng (400 ) mg/kg b.wt  and G4  was  treated with the aqueous extract of the Panax ginseng ( 400) mg/kg b.wt  after 3 hours given them lead acetate (150 mg/kg b. wt/day) for peroid 30 days . study aimed to determine the protective role of Panax ginseng extract on the antioxidants glutathione GSH and oxidants malondialdehyde (MDA) in the blood serum of male rabbits for 30 days. The result of present study showed: increase (P<0.05) in mean levels of glutathione (GSH) in the (G3) and (G4) group compare with Second group (positive control G2). decrease (P<0.05) in mean levels of malondialdehyde (MDA) in group (G3) and (G4) compare with Second group (positive control G2)

The protective effect of aqueous of Moringa Oleifera seeds extract against levofloxacin drug-induced liver damage in male white rats

Objective The goal of this study is to find out how effective Moringa seed (Moringa oleifera) aqueous Extract is in protecting liver tissue from oxidative stress caused by levofloxacin drug . Methods:    24 male albino rats were placed into four groups at random, with six rats in each group being treated for 30 days: Group 1 was a control group, whereas Group 2 was given levofloxacin at a dosage of 10 mg/kg orally by gavage. , The third group received aqueous extracts of   Moringa seeds 650 mg/kg, while the fourth group received aqueous extracts of Moringa seeds 650 mg/kg dose before 4 hours of receive orally at a 10 mg/kg per day dose . Results: The albino rat was considerably protected from levofloxacin-induced liver damage when given the aqueous extract Moringa seeds orally at a concentration of 650 mg/kg body weight. The action of the extract also protected the liver damage caused by the medication, which was indicated by congestion central vein degeneration hepatic cell, necrosis hepatic cell, irregular hepatocyte organization, dilatation and congestion of portal vein , Expandation of sinusoids and increased infiltration of inflammatory cells on histological examination.&nbsp

Effect of sesame oil on some blood parameters and antioxidants in ovariectomized female white rats

This study was conducted to find out the physiological effect of sesame seed oil (Sesamum indicum) in the case of oral treatment on post-menopause and the occurrence of surgical menopause as a result of the removal of the ovaries, by studying the changes in some blood parameters and some antioxidants in the serum of adult female rat pupae. White (Albino Rats), 15 adult rats about three months old, with weights ranging between 160-180 g, were used. The animals were randomly divided into three groups, five animals per group. The first group represented the negative control, which was normal without removing the ovaries, the second represented the positive control in which the ovaries were completely removed, and the third group had the ovaries completely removed and treated orally with sesame oil at a concentration of 4 ml/kg of body weight per day for a period of 30 days.&nbsp

A hormonal study of the effect of sesame oil in female albino rats whose ovaries had been removed

This study was conducted to investigate the physiological effect of sesame seed oil (Sesamum indicum) in the case of oral treatment on post-menopause and the occurrence of surgical menopause as a result of the removal of the ovaries, by studying the changes in some hormones in the blood serum of adult female albino rats (Albino Rats). as 15 adult rats about three months old, with weights ranging from 160-180 g were used. The animals were randomly divided into three groups with five animals for each group. The first group represented the negative control, which was normal without removal of the ovaries, and the second represented the positive control that was removed The ovaries were completely removed, and the third group completely removed the ovaries and treated them orally with sesame oil at a concentration of 4 ml/ kg of body weight per day for 30 days. The results of laboratory tests for serum samples of the completely removed ovaries group compared to the negative control group showed a significant decrease (P<0.05) in the levels of estrogen and progesterone, while an insignificant increase )P (0.05<in prolactin levels was observed, and significant (P<0.05) for follicle-stimulating hormone (FSH) and luteal stimulating hormone (LH).&nbsp

SARS-CoV-2 vaccination modelling for safe surgery to save lives: data from an international prospective cohort study

Background: Preoperative SARS-CoV-2 vaccination could support safer elective surgery. Vaccine numbers are limited so this study aimed to inform their prioritization by modelling. Methods: The primary outcome was the number needed to vaccinate (NNV) to prevent one COVID-19-related death in 1 year. NNVs were based on postoperative SARS-CoV-2 rates and mortality in an international cohort study (surgical patients), and community SARS-CoV-2 incidence and case fatality data (general population). NNV estimates were stratified by age (18-49, 50-69, 70 or more years) and type of surgery. Best- and worst-case scenarios were used to describe uncertainty. Results: NNVs were more favourable in surgical patients than the general population. The most favourable NNVs were in patients aged 70 years or more needing cancer surgery (351; best case 196, worst case 816) or non-cancer surgery (733; best case 407, worst case 1664). Both exceeded the NNV in the general population (1840; best case 1196, worst case 3066). NNVs for surgical patients remained favourable at a range of SARS-CoV-2 incidence rates in sensitivity analysis modelling. Globally, prioritizing preoperative vaccination of patients needing elective surgery ahead of the general population could prevent an additional 58 687 (best case 115 007, worst case 20 177) COVID-19-related deaths in 1 year. Conclusion: As global roll out of SARS-CoV-2 vaccination proceeds, patients needing elective surgery should be prioritized ahead of the general population