Echocardiographic findings in patients carrying the genetic variant associated with DCM.

<p>Gender: M, male; F, female. Symptoms: P, palpitations; T, transplanted; p-T, Pre-transplant stage; p-S, Presyncope; S, Syncope; SHF, sudden heart failure; (-) means no dyspnea. New York Heart Association Functional Classification is indicated by a rank between 1 and 4. LVEF indicates left ventricle ejection fraction; TDLVD, telediastolic left ventricle diameter; LAA1, left atrial volume; E/A ratio, relation between E-wave and A-wave in Doppler. Knock in myocardium is indicated by presence (1) or absence (0).</p

Microscopic images of post-mortem tissue.

<p>Pictures showed myofibrillar loss (A and C) and mild interstitial fibrosis (B and D). Nuclear pleomorphism and cellular atrophy is also observed (C). Hematoxylin-eosin labeling (A and C), and picro-Sirius Red labeling (B and D). Scale: A and B (200x) C and D (400x).</p