ROC Curves for the 5 genes commonly expressed: <i>FAMI3</i>, <i>IRAK3</i>, <i>DENND2D</i>, <i>PLBD1</i> and <i>AGPAT9</i>.

<p>Curves are provided for both Illumina and Affymetrix individual analyses as well as our integrative meta-analysis. The Area Under the Curve (AUC) metrics are also provided for each curve.</p

Coincident genes in the three analyzes: Affymetrix, Illumina and integrated meta-analysis.

<p>Coincident genes in the three analyzes: Affymetrix, Illumina and integrated meta-analysis.</p

Characteristics of both Cohort 1 and Cohort 2 groups of PDAC patients.

<p>Characteristics of both Cohort 1 and Cohort 2 groups of PDAC patients.</p

Comparison of individual analysis by technology with integrated analysis.

<p><b>a</b> Coincident genes in the three analyzes: Affymetrix, Illumina and integrated meta-analysis (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0194844#pone.0194844.t002" target="_blank">Table 2</a>). <b>b</b> Remaining differentially expressed genes in individual Illumina and the integrative meta-analysis (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0194844#pone.0194844.s006" target="_blank">S1 Table</a>). <b>c</b> Remaining differentially expressed genes in individual Affymetrix and the integrative meta-analysis (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0194844#pone.0194844.s007" target="_blank">S2 Table</a>). <b>d</b> Differentially expressed genes in the integrative meta-analysis but not in individual analysis (gained genes) (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0194844#pone.0194844.s008" target="_blank">S3 Table</a>).</p

Shared Gene Ontology (GO) terms after the gene enrichment analysis applied over the 28 gained genes.

<p>The Kolmogorov-Smirnov statistical test was performed to determine their significance (<i>p</i>-value < 0.05).</p

Principal Component Analysis (PCA) of the climatic space of Oman (grey dots) using 12 BIOCLIM variables.

<p>Dashed lines delimit the climatic clusters that group 10% of the explained variance by PC1 and PC2. Green dots represent the climatic space of protected areas.</p

Number of species displayed in a cumulative way.

<p>Dots represent the years with species descriptions. Dashed lines divide the graph into intervals of 20 years. The last dot includes the species in the process of being described.</p

Physical map of Oman.

<p>Map of Oman showing topographical relief and names of the most relevant toponyms mentioned in this study.</p

Maps of species richness.

<p>(A) Species richness by governorate; (B) species richness by grids of 10 arc-minutes of latitude and longitude.</p

Percentage of the species’ distribution area included within a protected area.

<p>Dashed lines indicate the conservation target of 17% and 12% of the total species’ distribution area within a protected area. (A) The extent of species occurrence was defined using the presence-absence in every pixel of 1 km x 1 km. (B) The extent of species occurrence was defined using a minimum convex polygon (MCP) of the observations filtered by the species’ average altitude.</p