Virologic treatment response of various categories of patients.

<p>Virologic treatment response of various categories of patients.</p

Peak nevirapine concentration is consistent with better adherence and viral load suppression.

<p>Peak nevirapine concentration is consistent with better adherence and viral load suppression.</p

Trajectory plasma nevirapine concentrations and association with viral load.

<p>Plasma nevirapine concentration (cNVP) is compared for various groups over 24 hour period according to adherence (A:- open circle, good adherence; closed diamonds, fair adherence; open triangle, poor adherence; solid line, mean), and according to virologic response or gender (B:- open diamond, virologic failure; closed circle, virologic success or non-virologic failure; closed triangle, male; crosses, female). Patients with good and fair adherence and those with virologic success (non-virologic failure) had peak cNVP at 4 hours while cNVP for virologic failure patients started low at 1hr and peaked later at 24hrs. Significant inverse correlations are observed between same day viral load with cNVP at 1 hour (C) and at 4 hours (D). Circles, virologic success; triangles, virologic failure.</p

Peak cNVP predict virologic response as much as does VL in a multivariate analysis.

<p>Peak cNVP predict virologic response as much as does VL in a multivariate analysis.</p