Molecular and classical cytogenetic analyses demonstrate an apomorphic reciprocal chromosomal translocation in Gorilla gorilla

The existence of an apomorphic reciprocal chromosomal translocation in the gorilla lineage has been asserted or denied by various cytogeneticists. We employed a new molecular cytogenetic strategy (chromosomal in situ suppression hybridization) combined with high-resolution banding, replication sequence analysis, and fluorochrome staining to demonstrate that a reciprocal translocation between ancestral chromosomes homologous to human chromosome 5 and 17 has indeed occurred

Orbital and Spin Excitations in Cobalt Oxide

By means of neutron scattering we have determined new branches of magnetic excitations in orbitally active CoO (TN=290 K) up to 15 THz and for temperatures from 6 K to 450 K. Data were taken in the (111) direction in six single-crystal zones. From the dependence on temperature and Q we have identified several branches of magnetic excitation. We describe a model for the coupled orbital and spin states of Co2+ subject to a crystal field and tetragonal distortion.Comment: To be published in Physica B (Proceedings of SCES07 conference in Houston

On the controversy concerning the definition of quark and gluon angular momentum

A major controversy has arisen in QCD as to how to split the total angular momentum into separate quark and gluon contributions, and as to whether the gluon angular momentum can itself be split, in a gauge invariant way, into a spin and orbital part. Several authors have proposed various answers to these questions and offered a variety of different expressions for the relevant operators. I argue that none of these is acceptable and suggest that the canonical expression for the momentum and angular momentum operators is the correct and physically meaningful one. It is then an inescapable fact that the gluon angular momentum operator cannot, in general, be split in a gauge invariant way into a spin and orbital part. However, the projection of the gluon spin onto its direction of motion i.e. its helicity is gauge invariant and is measured in deep inelastic scattering on nucleons. The Ji sum rule, relating the quark angular momentum to generalized parton distributions, though not based on the canonical operators, is shown to be correct, if interpreted with due care. I also draw attention to several interesting aspects of QED and QCD, which, to the best of my knowledge, are not commented upon in the standard textbooks on Field Theory.Comment: 41 pages; Some incorrect statements have been rectified and a detailed discussion has been added concerning the momentum carried by quarks and the Ji sum rule for the angular momentu

Radiative corrections to the Dalitz plot of K_{l3}^\pm decays

We calculate the model-independent radiative corrections to the Dalitz plot of K_{l3}^\pm decays to order (\alpha/\pi)(q/M_1), where q is the momentum transfer and M_1 is the mass of the kaon. The final results are presented, first, with the triple integration over the variables of the bremsstrahlung photon ready to be performed numerically and, second, in an analytical form. These two forms are useful to crosscheck on one another and with other calculations. This paper is organized to make it accessible and reliable in the analysis of the Dalitz plot of precision experiments and is not compromised to fixing the form factors at predetermined values. It is assumed that the real photons are kinematically discriminated. Otherwise, our results have a general model-independent applicability.Comment: RevTex4, 38 pages, 5 figures, 5 tables; some typos corrected; discussion extended to compare with other result

Quantitative profiling of selective Sox/POU pairing on hundreds of sequences in parallel by Coop-seq

© The Author(s) 2016. Published by Oxford University Press on behalf of Nucleic Acids Research. Cooperative binding of transcription factors is known to be important in the regulation of gene expression programs conferring cellular identities. However, current methods to measure cooperativity parameters have been laborious and therefore limited to studying only a few sequence variants at a time. We developed Coop-seq (cooperativity by sequencing) that is capable of efficiently and accurately determining the cooperativity parameters for hundreds of different DNA sequences in a single experiment. We apply Coop-seq to 12 dimer pairs from the Sox and POU families of transcription factors using 324 unique sequences with changed half-site orientation, altered spacing and discrete randomization within the binding elements. The study reveals specific dimerization profiles of different Sox factors with Oct4. By contrast, Oct4 and the three neural class III POU factors Brn2, Brn4 and Oct6 assemble with Sox2 in a surprisingly indistinguishable manner. Two novel half-site configurations can support functional Sox/Oct dimerization in addition to known composite motifs. Moreover, Coop-seq uncovers a nucleotide switch within the POU half-site when spacing is altered, which is mirrored in genomic loci bound by Sox2/Oct4 complexes.Link_to_subscribed_fulltex

Triple Compton effect: A photon splitting into three upon collision with a free electron

The process in which a photon splits into three after the collision with a free electron (triple Compton effect) is the most basic process for the generation of a high-energy multi-particle entangled state composed out of elementary quanta. The cross section of the process is evaluated in two experimentally realizable situations, one employing gamma photons and stationary electrons, and the other using keV photons and GeV electrons of an x-ray free electron laser. For the first case, our calculation is in agreement with the only available measurement of the differential cross section for the process under study. Our estimates indicate that the process should be readily measurable also in the second case. We quantify the polarization entanglement in the final state by a recently proposed multi-particle entanglement measure.Comment: 5 pages; RevTeX; to be published in Phys.Rev.Let

Von Neumann's 'No Hidden Variables' Proof: A Re-Appraisal

Since the analysis by John Bell in 1965, the consensus in the literature is that von Neumann's 'no hidden variables' proof fails to exclude any significant class of hidden variables. Bell raised the question whether it could be shown that any hidden variable theory would have to be nonlocal, and in this sense 'like Bohm's theory.' His seminal result provides a positive answer to the question. I argue that Bell's analysis misconstrues von Neumann's argument. What von Neumann proved was the impossibility of recovering the quantum probabilities from a hidden variable theory of dispersion free (deterministic) states in which the quantum observables are represented as the 'beables' of the theory, to use Bell's term. That is, the quantum probabilities could not reflect the distribution of pre-measurement values of beables, but would have to be derived in some other way, e.g., as in Bohm's theory, where the probabilities are an artefact of a dynamical process that is not in fact a measurement of any beable of the system.Comment: 8 pages, no figures; for Peter Mittelstaedt Festschrift issue of Foundations of Physic

Quantum Structures: An Attempt to Explain the Origin of their Appearance in Nature

We explain the quantum structure as due to the presence of two effects, (a) a real change of state of the entity under influence of the measurement and, (b) a lack of knowledge about a deeper deterministic reality of the measurement process. We present a quantum machine, where we can illustrate in a simple way how the quantum structure arises as a consequence of the two mentioned effects. We introduce a parameter epsilon that measures the size of the lack of knowledge on the measurement process, and by varying this parameter, we describe a continuous evolution from a quantum structure (maximal lack of knowledge) to a classical structure (zero lack of knowledge). We show that for intermediate values of epsilon we find a new type of structure, that is neither quantum nor classical. We apply the model that we have introduced to situations of lack of knowledge about the measurement process appearing in other regions of reality. More specifically we investigate the quantum-like structures that appear in the situation of psychological decision processes, where the subject is influenced during the testing, and forms some of his opinions during the testing process. Our conclusion is that in the light of this explanation, the quantum probabilities are epistemic and not ontological, which means that quantum mechanics is compatible with a determinism of the whole.Comment: 22 pages, 8 figure