Synthesis of biomedical Ti-25Ni-15Si-10HA alloy by mechanical alloying and spark plasma sintering

In this research approach, a β-phase titanium alloy was produced successfully employing mechanical alloying and consolidated with spark plasma sintering (SPS) process. Herein, Ni, Si and HA powders with varied weight percentage were used to fabricate the Ti alloy. The influence of HA addition on microstructure of the alloy was assessed using optical microscopy route and further amplified using field emission scanning electron microscopy (FESEM). The elemental composition and phase of Ti-alloy was investigated using x-ray diffractometer. Vicker hardness (HV) tester was employed to estimate the micro hardness of the specimen surface. During the FESEM analysis, it was observed that within the sintering process, alloy exhibits complex reactions with HA, which leads to the progress of bioactive compounds (CaO, TiO2, Ca3 (PO4)2, Ti2Ni, CaTiO3 and CaTiSiO5) enhancing the bioactivity of the Ti alloy. The fabricated Ti alloy (Ti-25Ni-15Si-10HA) exhibited superior microhardness (~458HV) at 900°C, comparative to the other alloys of the native category. Based upon the current investigation, Ti-25Ni-15Si-10HA alloy could find applications as bioimplants in dental and orthopedic areas

Synthesis of biomedical Ti-25Ni-15Si-10HA alloy by mechanical alloying and spark plasma sintering

In this research approach, a β-phase titanium alloy was produced successfully employing mechanical alloying and consolidated with spark plasma sintering (SPS) process. Herein, Ni, Si and HA powders with varied weight percentage were used to fabricate the Ti alloy. The influence of HA addition on microstructure of the alloy was assessed using optical microscopy route and further amplified using field emission scanning electron microscopy (FESEM). The elemental composition and phase of Ti-alloy was investigated using x-ray diffractometer. Vicker hardness (HV) tester was employed to estimate the micro hardness of the specimen surface. During the FESEM analysis, it was observed that within the sintering process, alloy exhibits complex reactions with HA, which leads to the progress of bioactive compounds (CaO, TiO2, Ca3 (PO4)2, Ti2Ni, CaTiO3 and CaTiSiO5) enhancing the bioactivity of the Ti alloy. The fabricated Ti alloy (Ti-25Ni-15Si-10HA) exhibited superior microhardness (~458HV) at 900°C, comparative to the other alloys of the native category. Based upon the current investigation, Ti-25Ni-15Si-10HA alloy could find applications as bioimplants in dental and orthopedic areas

Cost-benefit analysis of intervention policies for prevention and control of brucellosis in India

<div><p>Background</p><p>Brucellosis is endemic in the bovine population in India and causes a loss of US$3·4 billion to the livestock industry besides having a significant human health impact.</p><p>Methods</p><p>We developed a stochastic simulation model to estimate the impact of three alternative vaccination strategies on the prevalence of <i>Brucella</i> infection in the bovine populations in India for the next two decades: (a) annual mass vaccination only for the replacement calves and (b) vaccination of both the adult and young population at the beginning of the program followed by an annual vaccination of the replacement calves and, (c) annual mass vaccination of replacements for a decade followed by a decade of a test and slaughter strategy.</p><p>Findings</p><p>For all interventions, our results indicate that the prevalence of <i>Brucella</i> infection will drop below 2$ 4·16 billion for intervention (a), US $8·31 billion for intervention (b) and, US$ 4·26 for intervention (c). For buffalo, the corresponding NPVs were US $8·77 billion, US$ 13·42 and, US $ 7·66, respectively. The benefit cost ratio (BCR) for the first, second and the third intervention for cattle were 7·98, 10·62 and, 3·16, respectively. Corresponding BCR estimates for buffalo were 17·81, 21·27 and, 3·79, respectively.</p><p>Conclusion</p><p>These results suggest that all interventions will be cost-effective with the intervention (b), i.e. the vaccination of replacements with mass vaccination at the beginning of the program, being the most cost-effective choice. Further, sensitivity analysis revealed that all interventions will be cost-effective even at the 50% of the current prevalence estimates. The results advocate for the implementation of a disease control program for brucellosis in India.</p></div

Parameters used for benefit-cost analysis of intervention strategies to control brucellosis in bovine populations, India (1 US $ = Rs. 60/-).

<p>Parameters used for benefit-cost analysis of intervention strategies to control brucellosis in bovine populations, India (1 US $ = Rs. 60/-).</p

Net present value (NPV) and benefit-cost ratio (BCR) of a brucellosis intervention program in buffalo (first 20 years) in India.

<p>Scenario 1 –Vaccination of replacements; Scenario 2 –Vaccination for all at once followed by vaccination of replacements; Scenario 3 –Vaccination of replacements for the first 10 years followed by the test and cull for remaining 10 years.</p

Net present value (NPV) and benefit-cost ratio (BCR) of a brucellosis intervention program in cattle (first 20 years) in India.

<p>Scenario 1 –Vaccination of replacements; Scenario 2 –Vaccination for all at once followed by vaccination of replacements; Scenario 3 –Vaccination of replacements for the first 10 years followed by the test and cull for remaining 10 years.</p

A framework for selecting the location of very large photovoltaic solar power plants on a global/supergrid

One of the important optimization applications (minimization and maximization) is the power grid systems. National electricity grids should be interconnected to develop larger regional grids (supergrids), and further integrated to build up a worldwide grid (global grid) for minimizing consumption of natural resources and maximizing economical useful life, recycling rate, and effective usage of natural resources. These supergrids and global grid concepts can only be developed through detailed and organized supportive research studies. This research study aims to find, define, identify, describe and select location selection factors of very large photovoltaic solar power plant investments on a global grid and supergrid concepts. Grey systems theory, fuzzy (Type-1 and 2) theories, Mamdani’s type fuzzy rule-based system, Interpretive Structural Modelling (ISM), Impact Matrix Cross-Reference Multiplication Applied to a Classification (MICMAC) tool, and Political, Economic, Social and Technological (PEST) framework and its extensions (SLEPT, PESTEL, PESTLE, STEEPLE, STEEPLED, DESTEP, STEER) are concurrently used in this study. Eleven (11) criteria are presented for preliminary screening (i.e. C1: global horizontal irradiation (GHI), C2: governments supergrid integration policy, C3: supergrid business climate and conditions, C4: High Voltage Direct Current (HVDC) and High Voltage Alternating Current (HVAC) electrification grid infrastructure, C5: land use, allocation and availability, C6: geological conditions, C7: political, war, terror & security, C8: topographical conditions, C9: climatic conditions, C10: water availability conditions, C11: natural disaster/hazard conditions), and 191 factors are presented for pre-feasibility investment stages. Findings can directly be used or taken as a basis for further analysis by researchers and practitioners. Keywords: Fuzzy logic, Global grid, Interpretive structural modelling, MICMAC, PEST, Photovoltaic, Supergri

Changes in prevalence of brucellosis in buffaloes after the implementation of intervention programmes.

<p>Changes in prevalence of brucellosis in buffaloes after the implementation of intervention programmes.</p