2,855 research outputs found

    Second-order weak lensing from modified gravity

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    We explore the sensitivity of weak gravitational lensing to second-order corrections to the spacetime metric within a cosmological adaptation of the parameterized post-Newtonian framework. Whereas one might expect nonlinearities of the gravitational field to introduce non-Gaussianity into the statistics of the lensing convergence field, we show that such corrections are actually always small within a broad class of scalar-tensor theories of gravity. We show this by first computing the weak lensing convergence within our parameterized framework to second order in the gravitational potential, and then computing the relevant post-Newtonian parameters for scalar-tensor gravity theories. In doing so we show that this potential systematic factor is generically negligible, thus clearing the way for weak lensing to provide a direct tracer of mass on cosmological scales for a wide class of gravity theories despite uncertainties in the precise nature of the departures from general relativity.Comment: 13 pages, 1 figure; v2: minor edits to match the PRD accepted versio

    Assessing the Reliability of Template-Based Clustering for Tractography in Healthy Human Adults

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    Tractography is a non-invasive technique to investigate the brain’s structural pathways (also referred to as tracts) that connect different brain regions. A commonly used approach for identifying tracts is with template-based clustering, where unsupervised clustering is first performed on a template in order to label corresponding tracts in unseen data. However, the reliability of this approach has not been extensively studied. Here, an investigation into template-based clustering reliability was performed, assessing the output from two datasets: Human Connectome Project (HCP) and MyConnectome project. The effect of intersubject variability on template-based clustering reliability was investigated, as well as the reliability of both deep and superficial white matter tracts. Identified tracts were evaluated by assessing Euclidean distances from a dataset-specific tract average centroid, the volumetric overlap across corresponding tracts, and along-tract agreement of quantitative values. Further, two template-based techniques were employed to evaluate the reliability of different clustering approaches. Reliability assessment can increase the confidence of a tract identifying technique in future applications to study pathways of interest. The two different template-based approaches exhibited similar reliability for identifying both deep white matter tracts and the superficial white matter

    A spatio-temporal comparison of avian migration phenology using Citizen Science data

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    The effects of climate change have wide-ranging impacts on wildlife species and recent studies indicate that birds’ spring arrival dates are advancing in response to changes in global climates. In this paper, we propose a spatio-temporal approach for comparing avian first arrival data for multiple species. As an example, we analyze spring arrival data for two long-distance migrants (Rubythroated Hummingbird Archilochus colubris; and Purple Martin Progne subis) in eastern North America from 2001–2010 using Citizen Science data. The proposed approach provides researchers with a tool to compare mean arrival dates while accounting for spatial and temporal variability. Our results show that on average, Purple Martins arrive 29.95 to 31.84 days earlier than Ruby-throated Hummingbirds, but after accounting for this overall difference, spatial nuances exist whereby martins arrive earlier in the southern United States and migrate northward at a slower rate than hummingbirds. Differences were also noted in how climate and weather variables such as the North Atlantic Oscillation index, winter temperature, winter–spring precipitation, sampling effort, and altitude impacted migration dates. Our method may easily be generalized to analyze a broad range of temporal and spatial Citizen Scientists data to help better understand the ecological impacts of climate change

    Diffusion dispersion imaging: Mapping oscillating gradient spin-echo frequency dependence in the human brain.

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    PURPOSE: Oscillating gradient spin-echo (OGSE) diffusion MRI provides information about the microstructure of biological tissues by means of the frequency dependence of the apparent diffusion coefficient (ADC). ADC dependence on OGSE frequency has been explored in numerous rodent studies, but applications in the human brain have been limited and have suffered from low contrast between different frequencies, long scan times, and a limited exploration of the nature of the ADC dependence on frequency. THEORY AND METHODS: Multiple frequency OGSE acquisitions were acquired in healthy subjects at 7T to explore the power-law frequency dependence of ADC, the diffusion dispersion. Furthermore, a method for optimizing the estimation of the ADC difference between different OGSE frequencies was developed, which enabled the design of a highly efficient protocol for mapping diffusion dispersion. RESULTS: For the first time, evidence of a linear dependence of ADC on the square root of frequency in healthy human white matter was obtained. Using the optimized protocol, high-quality, full-brain maps of apparent diffusion dispersion rate were also demonstrated at an isotropic resolution of 2 mm in a scan time of 6 min. CONCLUSIONS: This work sheds light on the nature of diffusion dispersion in the healthy human brain and introduces full-brain diffusion dispersion mapping at clinically relevant scan times. These advances may lead to new biomarkers of pathology or improved microstructural modeling

    Mapping the subcortical connectome using in vivo diffusion MRI: Feasibility and reliability

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    Tractography combined with regions of interest (ROIs) has been used to non-invasively study the structural connectivity of the cortex as well as to assess the reliability of these connections. However, the subcortical connectome (subcortex to subcortex) has not been comprehensively examined, in part due to the difficulty of performing tractography in this complex and compact region. In this study, we performed an in vivo investigation using tractography to assess the feasibility and reliability of mapping known connections between structures of the subcortex using the test-retest dataset from the Human Connectome Project (HCP). We further validated our observations using a separate unrelated subjects dataset from the HCP. Quantitative assessment was performed by computing tract densities and spatial overlap of identified connections between subcortical ROIs. Further, known connections between structures of the basal ganglia and thalamus were identified and visually inspected, comparing tractography reconstructed trajectories with descriptions from tract-tracing studies. Our observations demonstrate both the feasibility and reliability of using a data-driven tractography-based approach to map the subcortical connectome in vivo

    Palaeomagnetic re-investigation of early permian rift basalts from the Baoshan block, SW China: Constraints on the site-of-origin of the gondwana-derived eastern cimmerian terranes

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    A palaeomagnetic investigation was carried out on a series of rift basalts (Woniusi Formation) that accumulated on the Baoshan block (SW China) in the Early Permian, the aim being to provide quantitative palaeogeographical information on the eastern Cimmerian terrane as it detached from eastern Gondwana. Reliable data were obtained from four locations/28 individual cooling units, and when combined with the findings of an earlier study (three locations/19 sites) indicate that breakup occurred at 41.9°S (with errors, 34.2-51.2°S). Using this information, we fit Baoshan against Gondwana within a narrow longitudinal belt close to where northeast Greater India and northwest Australia were once in close proximity. Furthermore, we suggest that Sibumasu (Simao-Burma-Malyasia-Sumatra; the largest of the eastern Cimmerian blocks) lay directly to the east, offshore of Australia; Qiangtang and Lhasa almost certainly sat to the west (off northern Greater India-SE Arabia), but we are uncertain as to their exact configuration. Our findings are compared with several rather different models that have been published in recent years. The new palaeomagnetic constraint highlights the flexibility authors currently have in reconstructing the region, principally because of the overall lack of similar high-quality data from the various blocks. We explain how new data could resolve these ambiguities, thereby offering more robust explanations for eastern Gondwana's late Palaeozoic development

    Noise and Bias In Square-Root Compression Schemes

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    We investigate data compression schemes for proposed all-sky diffraction-limited visible/NIR sky surveys aimed at the dark-energy problem. We show that lossy square-root compression to 1 bit pixel^(-1) of noise, followed by standard lossless compression algorithms, reduces the images to 2.5–4 bits pixel^(-1), depending primarily upon the level of cosmic-ray contamination of the images. Compression to this level adds noise equivalent to ≀ 10% penalty in observing time. We derive an analytic correction to flux biases inherent to the square-root compression scheme. Numerical tests on simple galaxy models confirm that galaxy fluxes and shapes are measured with systematic biases ≟ 10^-4 induced by the compression scheme, well below the requirements of supernova and weak gravitational lensing dark-energy experiments. In a related investigation, Vanderveld and coworkers bound the shape biases using realistic simulated images of the high-Galactic–latitude sky. The square-root preprocessing step has advantages over simple (linear) decimation when there are many bright objects or cosmic rays in the field, or when the background level will vary

    Characterization of chemical and bacterial concentrations in floor dust samples in southeast texas households

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    Indoor dust can be a major source of heavy metals, nutrients, and bacterial contamination in residential environments and may cause serious health problems. The goal of this research is to characterize chemical and bacterial contaminants of indoor, settled house dust in the Houston Metropolitan region. To achieve this, a total of 31 indoor dust samples were collected, along with household survey data, which were subsequently analyzed for elemental and bacterial concentrations. Microscopic and geospatial analysis was conducted to characterize and map potential hotspots of contamination. Interestingly Cd, Cr, Cu, Pb, and Zn concentrations of all 31 indoor dust samples were significantly enriched and exceeded soil background concentrations. Furthermore, As, Cd, Pb, and Zn concentrations in the dust samples were significantly correlated to the enteric bacterial load concentrations. Human health assessment revealed that cancer risk values via ingestion for Cd, Cr, and Ni were greater than the acceptable range. Of our 31 dust sample isolates, three Gram-negative and 16 Gram-positive pathogenic bacteria were identified, capable of causing a wide range of dis-eases. Our results demonstrate that both chemical and bacterial characterization of indoor dust coupled with spatial mapping is essential to assess and monitor human and ecological health risks
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