Electrodeposition of Co-Ni-MoxOy Powders: Part I. The Influence of Deposition Conditions on Powder Composition and Morphology

The Co-Ni-MoxOy powders were obtained electrochemically at a constant current density from ammonia electrolyte. Ni and Co were anomalously deposited, inducing Mo deposition, which cannot be deposited separately from aqueous solutions. The obtained Co-Ni-MoxOy powders were investigated by energy dispersive spectroscopy (EDS), X-ray diffraction (XRD), and scanning electon microscope (SEM) methods. Based on the obtained experimental results, it was concluded that the particle size of deposited powders is influenced by the chemical composition of the electrolyte and current density imposed. XRD results suggested that obtained powders were of amorphous structure, although a Co3Mo compound can be formed if certain experimental conditions are applied

Translation and validation of the Serbian primary biliary cholangitis-40 questionnaire.

To translate into Serbian and validate the Primary Biliary Cholangitis-40 (PBC-40) and PBC-27 questionnaires.Ninety-four consecutive outpatients with the diagnosis of PBC from three departments across two tertiary care institutions in Belgrade were enrolled from February to October 2016. Standard methodology for cultural adaption of healthcare related quality of life questionnaires was used, and included: a forward translation, backward translation and a pilot test of the Serbian PBC-40 on five patients who gave suggestions and comments. For evaluation of the questionnaires, acceptance was shown by the proportion of missing items and the internal consistency was assessed using Cronbach's α coefficient. The PBC-40 was self-administered under the supervision of an experienced hepatologist. The PBC-27 is a shorter version of the PBC-40.A total of 92 (97.9%) of the patients were females. The mean age was 59.26 ± 1.05 years and the average length of disease was 60.45 ± 48.314 months. The average PBC-40 score was 85.62 ± 30.46. The total time needed to complete the questionnaire ranged from 7 to 16 minutes. The proportion of missing items was 5.45% (205/3760). Cronbach's α for the entire scale was 0.93. Reliability for all of the domains of the PBC-40 was above 0.70, except for the domain "Symptoms" (α = 0.52). Overall reliability of the PBC-27 was α = 0.90. Domains "Dryness", "Symptoms" and "Fatigue" demonstrated reliability below α = 0.70.The Serbian PBC-40 is a valid and reasonably adequate for use in Serbian PBC patients. The PBC-40 is preferred over the PBC-27

Analysis and missing proportions of the 40 items of the PBC-40.

<p>Analysis and missing proportions of the 40 items of the PBC-40.</p

Reliability of the Serbian PBC-27 using Cronbach's α coefficient.

<p>Reliability of the Serbian PBC-27 using Cronbach's α coefficient.</p

Reliability of the Serbian PBC-40 using Cronbach's α coefficient.

<p>Reliability of the Serbian PBC-40 using Cronbach's α coefficient.</p

Pearson Correlation between individual domains of the PBC-40, Mayo Risk Score and Length of disease.

<p>Pearson Correlation between individual domains of the PBC-40, Mayo Risk Score and Length of disease.</p

Demographic and clinical characteristics of the patients (n = 94).

<p>Demographic and clinical characteristics of the patients (n = 94).</p

Protective ventilation with high versus low positive end-expiratory pressure during one-lung ventilation for thoracic surgery (PROTHOR): study protocol for a randomized controlled trial

Background: Postoperative pulmonary complications (PPC) may result in longer duration of in-hospital stay and even mortality. Both thoracic surgery and intraoperative mechanical ventilation settings add considerably to the risk of PPC. It is unclear if one-lung ventilation (OLV) for thoracic surgery with a strategy of intraoperative high positive end-expiratory pressure (PEEP) and recruitment maneuvers (RM) reduces PPC, compared to low PEEP without RM. Methods: PROTHOR is an international, multicenter, randomized, controlled, assessor-blinded, two-arm trial initiated by investigators of the PROtective VEntilation NETwork. In total, 2378 patients will be randomly assigned to one of two different intraoperative mechanical ventilation strategies. Investigators screen patients aged 18 years or older, scheduled for open thoracic or video-assisted thoracoscopic surgery under general anesthesia requiring OLV, with a maximal body mass index of 35 kg/m2, and a planned duration of surgery of more than 60 min. Further, the expected duration of OLV shall be longer than two-lung ventilation, and lung separation is planned with a double lumen tube. Patients will be randomly assigned to PEEP of 10 cmH2O with lung RM, or PEEP of 5 cmH2O without RM. During two-lung ventilation tidal volume is set at 7 mL/kg predicted body weight and, during OLV, it will be decreased to 5 mL/kg. The occurrence of PPC will be recorded as a collapsed composite of single adverse pulmonary events and represents the primary endpoint. Discussion: PROTHOR is the first randomized controlled trial in patients undergoing thoracic surgery with OLV that is adequately powered to compare the effects of intraoperative high PEEP with RM versus low PEEP without RM on PPC. The results of the PROTHOR trial will support anesthesiologists in their decision to set intraoperative PEEP during protective ventilation for OLV in thoracic surgery. Trial registration: The trial was registered in clinicaltrials.gov (NCT02963025) on 15 November 2016