The development of number of binding sites in the brain of PRiMA WT and PRiMA KO mice.

<p>Abscissa: day of the development (E18.5, embryonal day 18.5; P0, postnatal day 0; P9, postnatal day 9; P30, postnatal day 30; P120, postnatal day 120; P425, postnatal day 425). Ordinate: the number of muscarinic receptor binding sites expressed as Bmax [fmol/mg protein]. ***p<0.001, significantly different from PRiMA +/+. ^#p<0.05, significantly different from previous day of development, ^##p<0.01, significantly different from previous day of development. ^###p<0.001 significantly different from previous day of development.</p