Candidate genes resulting from the 180-line GWAS on 2.0 μg/g and the 37-line GWAS.

<p>Candidate genes resulting from the 180-line GWAS on 2.0 μg/g and the 37-line GWAS.</p

Manhattan plots for the three GWAS.

<p>A) 37-line GWAS using LC₅₀ values, B) 180-line GWAS on 2.0 μg/g α-amanitin, C) 180-line GWAS on 0.2 μg/g α-amanitin. Selected significant gene names are printed on the top right of the corresponding dots in the graphs.</p

Larval viability variation in the DGRP lines in response to α-amanitin.

<p>The y-axis shows individual viability values, while the x-axis represents the individual DGRP lines. The lines are sorted from lowest α-amanitin resistance (left) to highest α-amanitin resistance (right). The error bars represent the standard error of the mean (SEM). A) 180 lines tested on 0.2 μg/g α-amanitin. (Individual line numbers are not shown but can be found in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0173162#pone.0173162.s001" target="_blank">S1 Table</a>). The y-axis represents the average number of flies hatched from 10 larvae placed on toxic food. B) 180 lines tested on 2.0 μg/g α-amanitin. (Individual line numbers are not shown but can be can be found in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0173162#pone.0173162.s001" target="_blank">S1 Table</a>). The y-axis represents the average hatch counts out of 10 larvae placed on toxic food. C). The y-axis represents the LC₅₀ values of the 37-line subset. The line numbers are shown on the x-axis.</p