Families in comparison: An individual-level comparison of life-course and family reconstructions between population and vital event registers

It remains unknown how different types of sources affect the reconstruction of life courses and families in large-scale databases increasingly common in demographic research. Here, we compare family and life-course reconstructions for 495 individuals simultaneously present in two well-known Dutch data sets: LINKS, based on the Zeeland province’s full-population vital event registration data (passive registration), and the Historical Sample of the Netherlands (HSN), based on a national sample of birth certificates, with follow-up of individuals in population registers (active registration). We compare indicators of fertility, marriage, mortality, and occupational status, and conclude that reconstructions in the HSN and LINKS reflect each other well: LINKS provides more complete information on siblings and parents, whereas the HSN provides more complete life-course information. We conclude that life-course and family reconstructions based on linked passive registration of individuals constitute a reliable alternative to reconstructions based on active registration, if case selection is carefully considered

Determining the Energy Barrier for Decay out of Superdeformed Bands

An asymptotically exact quantum mechanical calculation of the matrix elements for tunneling through an asymmetric barrier is combined with the two-state statistical model for decay out of superdeformed bands to determine the energy barrier (as a function of spin) separating the superdeformed and normal-deformed wells for several nuclei in the 190 and 150 mass regions. The spin-dependence of the barrier leading to sudden decay out is shown to be consistent with the decrease of a centrifugal barrier with decreasing angular momentum. Values of the barrier frequency in the two mass regions are predicted.Comment: v1: 4 pages, 1 figure, 1 table. v2: 5 pages, 1 figure, 1 table; minor corrections and clarification

Spectroscopy of neutron-deficient nuclei near the Z=82 closed shell via symmetric fusion reactions

In-beam and decay-spectroscopy studies of neutron-deficient nuclei near the Z=82 shell closure were carried out using the Fragment Mass Analyzer (FMA) and the Gammasphere array, in conjunction with symmetric fusion reactions and the Recoil Decay Tagging (RDT) technique. The primary motivation was to study properties of 179Tl and 180Tl, and their daughter, and grand-daughter isotopes. For the first time, in-beam structures associated with 179Tl and 180Tl were observed, as well as γ rays associated with the 180Tl α decay. No long-lived isomer was identified in 180Tl, in contrast with the known systematics for the heavier odd-odd Tl isotopes

Spin ∼ 60 ℏ in 156Dy: Competition between collective and terminating structures at very high-spin

The highest-spin discrete states (I ∼ 60 ℏ and Ex ∼ 30 MeV) in normal deformed nuclei have been observed in the rare-earth isotope 156Dy using the 124Sn(36S,4n) reaction in conjunction with the GAMMASPHERE spectrometer. The positive parity yrast sequence appears to evolve smoothly from a prolate (collective) towards an oblate (non-collective) shape, in contrast to the sudden shape change observed in the isotone 158Er. Terminating states are identified in the negative parity sequences at Iπ = 52- and 53- and specific multi-particle-hole configurations are assigned by comparison with cranked Nilsson-Strutinsky calculations. An order of magnitude increase in the interaction strength between close lying high-spin weakly collective structures is determined compared with that found in the lower-spin strongly collective domain. These results give valuable insight into the interplay between collective and terminating structures, and their competition for yrast status in the 40 - 60 ℏ spin range

γ-ray spectroscopy of proton neutron-hole nucleus 208Bi from deep inelastic heavy ion reactions

γ rays in the πν-1 nucleus 208Bi have been studied at the Gammasphere using deep-inelastic reactions induced by a 305-MeV 48Ca beam on a thick 208Pb target. Previously unknown yrast γ-ray cascades above the 10- millisecond isomer in 208Bi were identified in cross coincidence with known γ rays from complementary potassium products. Yrast and near-yrast levels up to 5.6 MeV in 208Bi have been located, and they are interpreted in light of earlier charged particle spectroscopy results, and with the help of shell model calculations

Diabetic gastroparesis: Therapeutic options

Gastroparesis is a condition characterized by delayed gastric emptying and the most common known underlying cause is diabetes mellitus. Symptoms include nausea, vomiting, abdominal fullness, and early satiety, which impact to varying degrees on the patient’s quality of life. Symptoms and deficits do not necessarily relate to each other, hence despite significant abnormalities in gastric emptying, some individuals have only minimal symptoms and, conversely, severe symptoms do not always relate to measures of gastric emptying. Prokinetic agents such as metoclopramide, domperidone, and erythromycin enhance gastric motility and have remained the mainstay of treatment for several decades, despite unwanted side effects and numerous drug interactions. Mechanical therapies such as endoscopic pyloric botulinum toxin injection, gastric electrical stimulation, and gastrostomy or jejunostomy are used in intractable diabetic gastroparesis (DG), refractory to prokinetic therapies. Mitemcinal and TZP-101 are novel investigational motilin receptor and ghrelin agonists, respectively, and show promise in the treatment of DG. The aim of this review is to provide an update on prokinetic and mechanical therapies in the treatment of DG