Ticks, demographics, vegetation cover, and farmer’s age influence red meat production in resource-poor regions of Eastern Cape Province of South Africa

This study presents an integrated examination of livestock production constraints associating with communal farming in six district municipalities (DMs) of the Eastern Cape Province. We collected data on demographic and socio-economic factors from 271 farmers randomly given questionnaires. About 26 Land Redistribution for Agricultural Development (LRAD) owned by communal farmers were surveyed to ascertain the condition of grazing land, meanwhile, tick species and distribution on cattle and goats found in 158 sampling sites of the study area were also recorded. From the results, a total of 34,929 adult ticks belonging to five genera and 10 species were encountered. The most abundant tick genera were Rhipicephalus of the subgenus Boophilus (68.91%), Amblyomma (20.72%), Hyalomma (8.64%), Ixodes (1.22%), and Haemaphysalis (0.51%). By geographic distributions, Am-blyomma and Rhipicephalus were common to all DMs, while R. microplus and R. decoloratus were found in the drier regions. From the map plotted for 16 custom feeding centers, lack of marketing channels (23%), poor animal conditions (20%), lack of infrastructure (19%), high price of medicine (14%), shortage of feed (10%), stock theft (8%), and age of animals (too old) to be marketed (6%) are the major shortcomings in red meat production. We found that the associations between gender (χ 2 = 31.3481, p < 0.0001), age (χ 2 = 32.4889, p < 0.0001), and farming experience (χ 2 = 52.7556, p < 0.0001) were significantly (p < 0.05) higher. Additionally, we found that farming commodities were significantly influenced by gender and farming experience. From the surveyed LRAD farms, we observed a higher proportion of increaser II grass species in Alfred Nzo (55.6%), Amathole (53.9%), and Chris Hani (46.4%) DMs. On the other hand, the decreaser grass species were few in Alfred Nzo (16.5%), Amathole (13.8%), and Chris Hani (21.8%). Inferences from the data indicate the need for government and stakeholders’ intervention to farmers through the provision of infrastructures, marketing channels, and training on livestock based programs.http://www.scirp.org/journal/ojasam2022Veterinary Tropical Disease

Point-of-care viral load testing to manage HIV viraemia during the rollout of dolutegravir-based ART in South Africa: a randomised feasibility study (POwER)

Background: Data is required regarding the feasibility of conducting a randomised trial of point-of-care viral load (VL) testing to guide management of HIV viraemia, and to provide estimates of effect to guide potential future trial design. Setting: Two public South African clinics during the dolutegravir-based antiretroviral therapy (ART) rollout. Methods: We randomised adults receiving first-line ART, with recent VL ≥1000 copies/mL, in a 1:1 ratio to receive point-of-care Xpert HIV-1 VL versus standard-of-care laboratory VL testing, after 12 weeks. Feasibility outcomes included proportions of eligible patients enrolled and completing follow-up, and VL process outcomes. Estimates of effect were assessed using the trial primary outcome of VL <50 copies/mL after 24 weeks. Results: From August 2020-March 2022 we enrolled 80 eligible participants, an estimated 24% of those eligible. 47/80 (58.8%) were women, and median age was 38.5 years (IQR 33-45). 44/80 (55.0%) were receiving dolutegravir and 36/80 (465.0%) were receiving efavirenz. After 12 weeks, point-of-care participants received VL results after median 3.1 hours (IQR 2.6-3.8), versus 7 days (IQR 6-8, p<0.001) in standard-of-care. 12-week follow-up VL was ≥1000 copies/mL in 13/39 (33.3%) point-of-care participants and in 16/41 (39.0%) standard-of-care participants; 11/13 (84.6%) and 12/16 (75.0%) switched to second-line ART respectively. After 24 weeks, 76/80 (95.0%) completed follow-up. 27/39 (69.2% [95%CI 53.4-81.4]) point-of-care participants achieved VL <50 copies/ml versus 29/40 (72.5% [57.0-83.9]) standard-of-care participants. Point-of-care participants had median 3 (IQR 3-4) clinic visits versus 4 (IQR 4-5) in standard-of-care (p<0.001). Conclusions: It was feasible to conduct a trial of point-of-care VL testing to manage viraemia. Point-of-care VL lead to quicker results and fewer clinical visits, but estimates of 24-week VL suppression were similar between arms

Get with the guidelines: management of chronic obstructive pulmonary disease in emergency departments in Europe and Australasia is sub‐optimal

International audienc