37 research outputs found
AR-quiver approach to affine canonical basis elements
AbstractThis is the continuation of [Y. Li, Affine quivers of type A˜n and canonical bases, math.QA/0501175]. We describe the affine canonical basis elements in the case when the affine quiver has arbitrary orientation. This generalizes the description in [G. Lusztig, Affine quivers and canonical bases, Publ. Math. Inst. Hautes Études Sci. 76 (1992) 111–163]
Results of viral testing from 90 patients suspected of having an infectious hepatitis.
<p>Results of viral testing from 90 patients suspected of having an infectious hepatitis.</p
Dengue virus infection among long-term travelers from the Netherlands: A prospective study, 2008-2011
<div><p>Background</p><p>Dengue is increasing rapidly in endemic regions. Data on incidence among travelers to these areas are limited. Five prospective studies have been performed thus far, mainly among short-term travelers.</p><p>Objective</p><p>To obtain the attack and incidence rate (AR, IR) of dengue virus (DENV) infection among long-term travelers and identify associated risk factors.</p><p>Methods</p><p>A prospective study was performed among long-term travelers (12–52 weeks) attending the Public Health Service in Amsterdam. Clients planning to travel to (sub)tropical countries were invited to participate. Participants kept a travel diary, recording itinerary, symptoms, and physician visits. Pre- and post-travel blood samples were serologically tested for the presence of Anti-DENV IgG antibodies. Seroconversion was considered suggestive of a primary DENV infection. Anti-DENV IgG present in both corresponding samples in combination with a post-/pre-travel ratio of ≥4:1 was suggestive of a secondary infection. Risk factors for a DENV infection were studied using poisson regression.</p><p>Results</p><p>In total, 600 participants were included; median age was 25 years (IQR: 23–29), 35.5% were male, and median travel duration was 20 weeks (IQR: 15–25). In 39 of 600 participants (AR: 6.5%; 95% CI 4.5–8.5%) anti-DENV IgG test results were suggestive of a recent infection, yielding an IR of 13.9 per 1,000 person-months traveling (95%CI: 9.9–19.1). No secondary infections were found. IR for Asia, Africa, and America were comparable and 13.5, 15.8, and 13.6 per 1,000 person-months respectively. Of participants with a recent DENV infection, 51% did not report dengue-like illness (DLI) or fever, but 10% were hospitalized. In multivariable analysis, travelers who seroconverted were significantly more likely to be vaccinated with ≥2 flavivirus vaccines for the current trip or to have reported DLI in >1 consecutive weeks.</p><p>Conclusions</p><p>Long-term travelers are at substantial risk of DENV infection. Half of those with a DENV infection reported no symptoms, but 10% were hospitalized, demonstrating the importance of advising anti-mosquito measures during travel.</p></div
Characteristics of 600 long-term travelers to dengue-endemic areas attending a Dutch travel health clinic for pre-travel advice including their incidence rates and risk factors of suggestive recent dengue virus infection, December 2008 –September 2011.
<p>Characteristics of 600 long-term travelers to dengue-endemic areas attending a Dutch travel health clinic for pre-travel advice including their incidence rates and risk factors of suggestive recent dengue virus infection, December 2008 –September 2011.</p
Characteristics of 600 long-term travelers attending a Dutch travel health clinic for pre-travel advice including prevalence and determinants of previous dengue infection, December 2008 –September 2011.
<p>Characteristics of 600 long-term travelers attending a Dutch travel health clinic for pre-travel advice including prevalence and determinants of previous dengue infection, December 2008 –September 2011.</p
Distribution of sex for each genotype plotted by spontaneous HCV clearance rate.
<p>Genotyping was available for 100/106 participants. Bars represent the total percentage of spontaneous HCV clearance for the protective alleles (TT for rs8099917 and CC for rs12979860) and non-protective alleles (CT/GG for rs8099917 and CT/TT for rs12979860). The numbers in the bars indicate the percentage of spontaneous HCV clearance for males and females for each allele.</p
Multivariate analysis of factors associated with HCV clearance in a cohort of 106 individuals with acute HCV acquired through injection drug use.
<p>Multivariate analysis of factors associated with HCV clearance in a cohort of 106 individuals with acute HCV acquired through injection drug use.</p
Univariate analysis of host genetic factors and viral coinfections associated with HCV clearance in a cohort of 106 individuals with acute HCV acquired through injection drug use.
<p>HBV, hepatits B virus; HCV, hepatitis C virus; HBc, hepatitis B core; HBsAG, Hepatitis B surface Antigen; IL28B, Interleukin 28B.</p
Univariate analysis of sociodemographic factors, behavioral factors and clinical symptoms associated with HCV clearance in a cohort of 106 individuals with acute HCV acquired through injection drug use.
<p>Univariate analysis of sociodemographic factors, behavioral factors and clinical symptoms associated with HCV clearance in a cohort of 106 individuals with acute HCV acquired through injection drug use.</p
HCV-1b NS3 UDPS mutation analysis.
<p>Percentage of UDPS reads with mutations. The parenthetical values indicate the number of reads analyzed. The bold numbers indicate variation present at a frequency above 0.1%. Underlined amino acids indicate resistant variants that were also observed by clonal sequencing at EOT. UDPS of both fragments (NS3-I, NS3-II) failed for patient 6 at both baseline and follow-up.</p