Schematic of experimental design.

Schematic of experimental design.</p

Percent of animals with ECM-B material present in the tibiofemoral joint at the time of harvest.

Each ECM-B joint is seen in variable tones of gray and Week 8 control samples are black.</p

Comparison of histology scores between ECM-B and PBS-treated control animals at eight weeks after treatment.

Mean scores ± standard error are presented.</p

Hind limb BOS of ECM-B and control animals from pre-procedure to Week 8 post-injection.

Circles represent means of the control group and squares represent ECM-B group means. The error bars represent the standard error. Mean and standard error values can be seen in the table to the right of the graph. Significantly different means are denoted by an asterisk in the graph and bolded in the table.</p

Parameters utilized to assess gait in statistical analyses.

All four limbs were individually assessed (i.e., Right front limb, left hind limb).</p

Mean gait parameter value of each group at each time point with standard error.

Significant P values (P adj. < .05) are bolded. Each group contains n = 5 animals except for week 8 ECM-B where n = 6. All values are presented as the mean± standard error.</p