15,392 research outputs found

    Paramagnetic state in d-wave Superconductors

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    We study theoretically the paramagnetic state in d-wave superconductors. We present the specific heat, the magnetization, superfluid density obtained within the weak-coupling model. At low temperatures and for small magnetic fields they exhibit simple power law behaviors, which should be accessible experimentally in hole-doped high-T_c cuprates and \kappa-(ET)_2 salts in a magnetic field within the conducting plane.Comment: 5 pages(EuroTeX), 13 figures, submitted to Europhysics Letter

    Surface immobilization of hexa-histidine-tagged adeno-associated viral vectors for localized gene delivery.

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    Adeno-associated viral (AAV) vectors, which are undergoing broad exploration in clinical trials, have significant promise for therapeutic gene delivery because of their safety and delivery efficiency. Gene delivery technologies capable of mediating localized gene expression may further enhance the potential of AAV in a variety of therapeutic applications by reducing spread outside a target region, which may thereby reduce off-target side effects. We have genetically engineered an AAV variant capable of binding to surfaces with high affinity through a hexa-histidine metal-binding interaction. This immobilized AAV vector system mediates high-efficiency delivery to cells that contact the surface and thus may have promise for localized gene delivery, which may aid numerous applications of AAV delivery to gene therapy

    Production and optical properties of liquid scintillator for the JSNS2^{2} experiment

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    The JSNS2^{2} (J-PARC Sterile Neutrino Search at J-PARC Spallation Neutron Source) experiment will search for neutrino oscillations over a 24 m short baseline at J-PARC. The JSNS2^{2} inner detector will be filled with 17 tons of gadolinium-loaded liquid scintillator (LS) with an additional 31 tons of unloaded LS in the intermediate γ\gamma-catcher and outer veto volumes. JSNS2^{2} has chosen Linear Alkyl Benzene (LAB) as an organic solvent because of its chemical properties. The unloaded LS was produced at a refurbished facility, originally used for scintillator production by the RENO experiment. JSNS2^{2} plans to use ISO tanks for the storage and transportation of the LS. In this paper, we describe the LS production, and present measurements of its optical properties and long term stability. Our measurements show that storing the LS in ISO tanks does not result in degradation of its optical properties.Comment: 7 pages, 4 figures
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