Comparison of metabolites obtained by ¹H-NMR spectroscopy between patient groups classified by the presence of lymph node metastasis and lateral lymph node metastasis.

<p>Comparison of metabolites obtained by ¹H-NMR spectroscopy between patient groups classified by the presence of lymph node metastasis and lateral lymph node metastasis.</p

Patient demographics and clinicopathologic characteristics.

<p>Patient demographics and clinicopathologic characteristics.</p

Application of metabolomics in prediction of lymph node metastasis in papillary thyroid carcinoma - Fig 1

<p>(Left) OPLA-DA score plot for lymph node metastasis. Red dots represent patients with lymph node metastasis and black dots represents patient without lymph node metastasis. The x-axis is the first component from OPLS-DA and the y-axis is the corresponding orthogonal score. (Right) OPLS-DS loading S-plot for lymph node metastasis. The x-axis is the covariation and the y-axis is the corresponding orthogonal score. The metabolites situated at the upper right or lower left sections are statistically relevant and represent possible discriminating variables.</p

Application of metabolomics in prediction of lymph node metastasis in papillary thyroid carcinoma - Fig 2

<p>(Left) OPLA-DA score plot for lateral lymph node metastasis. Red dots represent patients with lateral lymph node metastasis and black dots represents patient without lateral lymph node metastasis. The x-axis is the first component from OPLS-DA and the y-axis is the corresponding orthogonal score. (Right) OPLS-DS loading S-plot for lateral lymph node metastasis. The x-axis is the covariation and the y-axis is the corresponding orthogonal score. The metabolites situated at the upper right or lower left sections are statistically relevant and represent possible discriminating variables.</p