Heat map depicting clustering proportions of individuals sequenced 34 clusters (n = 283) stratified by baseline characteristics.

<p>The x-axis represents district, uc is un-clustered, c is clustered. The columns list on the y-axis are individual characteristics at study initiation and subsequent columns are the proportions clustered or un-clustered by district. Proportions are shown as a heat map to represent increasing proportions. Cells were colour coded with sliding colours as follows: blue corresponds to a low number of clustering, yellow corresponds to an intermediate amount of clustering and red corresponds to high level of clustering. Note that individuals in Masaka, Wakiso and Mukono; 2,2,1 had missing age, 25,3,1, had duration resident in area missing, 2,2,1 had missing marital status, 24,3,1 had missing occupation, 7,3,1 had alcohol use missing, 11,9,1 had partnerships missing, 7,3,1 had away 3 months missing and the remaining characteristics had none missing.</p

Characteristics of sequenced data 34 clusters (n = 283).

<p>Characteristics of sequenced data 34 clusters (n = 283).</p

HIV sequences from HIV-infected Individuals in fisherfolk high-risk fishing communities (n = 283).

<p>HIV sequences from HIV-infected Individuals in fisherfolk high-risk fishing communities (n = 283).</p

Discrete location of individuals with identified HIV clusters and gender.

<p>In all figures, the gender is indicated by shape: square = female, circle = male. Non-sequenced is indicated by grey colour, and sequenced of the non-clustered individuals is indicated by yellow. Cluster memberships are indicated by colours other than grey and yellow: the individuals here share the same colour if and only if they belong to the same cluster. Filled circles/squares are incident cases, while non-filled ones are prevalent cases. In the figure, the location of each household is randomly allocated within the corresponding village (Masaka district (Lambu, Kamuwungu), Mukono district (Nsadzi), Wakiso district (Kasenyi, Nakiwogo). Household membership, gender and prevalent or incident HIV status of the HIV infected individuals are presented by village and by gene region.</p

Maximum-likelihood phylogenetic tree showing the HIV transmission clusters in <i>env</i> gene approximately 460 base pairs (n = 22) involving 79 of the 266 participant sequences shown while the rest of clusters had two members.

<p>One cluster with bootstrap of 99% and genetic distance of ≤ 4.5% is included since it clustered in <i>gag</i>. Subtype A clusters are highlighted red, subtype C purple and subtype D blue. The tree scale is shown.</p

Characteristics of 34 clusters identified in <i>gag</i> or <i>env</i> gene regions for 283 HIV-infected participants 2009–2011.

<p>Characteristics of 34 clusters identified in <i>gag</i> or <i>env</i> gene regions for 283 HIV-infected participants 2009–2011.</p

Maximum-likelihood phylogenetic tree showing the HIV transmission clusters in <i>gag</i> gene approximately 463 base pairs (n = 25) involving 86 of the 276 participant sequences.

<p>Clusters with bootstrap support ≥ 95% and genetic distance of ≤ 3.5% are shown. Three clusters with > 2 members are shown while the rest of clusters had two members. Subtype A clusters are highlighted red and subtype D blue. The tree scale is shown.</p

Enrolment of study participants.

<p>Enrolment of study participants.</p

Summary of baseline characteristics for the 3 lakeshore districts surveyed in 5 fishing communities between 2009–2011.

<p>Summary of baseline characteristics for the 3 lakeshore districts surveyed in 5 fishing communities between 2009–2011.</p

Study profile: Of the 427 participants screened, 425 were enrolled and started on ART at the three sites.

<p>Three hundred and twenty one participants completed their 12 months visit and had viral load results available at baseline and month 12. Forty nine had viral loads equal or above 1000 copies/ml and were genotyped. Of these 35 participants had HIV drug resistance mutations.</p