Neurolysis for ulnar nerve compression syndrome: a surgical technique for outpatients

Submitted by Ana Maria Fiscina Sampaio ([email protected]) on 2016-08-15T13:57:07Z No. of bitstreams: 1 Jambeiro Gorge ES Neurolise externa ....pdf: 447595 bytes, checksum: 49b1b8a04934d655844b61bfc804de76 (MD5)Approved for entry into archive by Ana Maria Fiscina Sampaio ([email protected]) on 2016-08-15T14:11:50Z (GMT) No. of bitstreams: 1 Jambeiro Gorge ES Neurolise externa ....pdf: 447595 bytes, checksum: 49b1b8a04934d655844b61bfc804de76 (MD5)Made available in DSpace on 2016-08-15T14:11:50Z (GMT). No. of bitstreams: 1 Jambeiro Gorge ES Neurolise externa ....pdf: 447595 bytes, checksum: 49b1b8a04934d655844b61bfc804de76 (MD5) Previous issue date: 1997Escola Bahiana de Medicina e Saúde Pública. Salvador, BA, Brasil / Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, BrasilRibotEscola Bahiana de Medicina e Saúde Pública. Salvador, BA, BrasilRibotFundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, BrasilEscola Bahiana de Medicina e Saúde Pública. Salvador, BA, BrasilApresenta-se uma técnica cirúrgica de neurólise externa do nervo ulnar com o uso de anestesia local e sem isquemia peroperatória. Crê-se que este procedimento representa boa opção de uso no tratamento ambulatorial em longa escala da neuropatia do nervo ulnar, especialmente em pacientes com hanseníaseThe authors present a simplified surgical technique for the treatment of ulnar compressive syndrome by using local anesthesia without ischemia in the neurolysis of the nerve. This procedure represents a new perspective as an outpatient surgery in the massive therapy of the handicapped, especially in Hansen’s disease

Treatment with benznidazole in association with immunosuppressive drugs in mice chronically infected with Trypanosoma cruzi: investigation into the possible development of neoplasias

Benznidazole is recommended in Brazil for the treatment of Trypanosoma cruzi infection in acute and early chronic phases of Chagas' disease. Observations by others have indicated a higher incidence of neoplasias in immunosuppressed patients, presenting Chagas' disease reactivation, submitted to treatment with benznidazole. In the present study, we investigated whether there is a potentiation in the generation of lymphomas in chronically infected mice, treated with immunosuppressive drugs and benznidazole. For this, 142 Swiss mice chronically infected with the 21 SF strain of T. cruzi and 72 normal Swiss mice were used. Both infected and normal mice were divided into experimental groups and submitted to one of the following treatment regimens: benznidazole alone; immunosuppressive drugs (azathioprine, betamethasone and cyclosporin); a combination of immunosuppressive drugs and benznidazole; and untreated controls. In the infected group treated with benznidazole, one mouse developed a non-Hodgkin's lymphoma. This finding has been interpreted as a spontaneous tumor of mice. The study of the chronically infected mice treated with the combination of immunosuppressive drugs and benznidazole demonstrated an absence of lymphomas or other neoplasias. These findings support the indication of benznidazole, as the drug of choice, for immunosuppressed patients that develop a reactivation of Chagas' disease