Drug resistance mutation detection in limiting dilution series.

<p>Two HIV-1 subtype B samples were used for the dilution series (A, samples 40–44; B, samples 45–49). The four groups shown in the histogram are based on the median frequency of each drug resistance mutation in its respective <i>undiluted</i> sample: >20% (white bars), 10–20% (bright grey bars), 2–10% (dark grey bars), and 1–2% (black bars). The means and standard deviations are given of the percentage of sites reporting drug-resistance mutations in these categories. The number of mutations in each category is represented by n.</p

Global Methane Cycle

<p>Methane is oxidized either photochemically in the atmosphere or biologically in terrestrial and aquatic systems. The ocean, grasslands, and desert form major methane sinks, whereas wetlands, agricultural and grazing lands, and other anthropogenic sources such as landfills, are major sources. The cow depicted in the figure represents diverse ruminants. Anthropogenic inputs of nitrogen in the form of ammonia compete for MMOs, reducing methane oxidation and leading to the formation of nitrous oxide, another greenhouse gas.</p

Predicted Central Metabolic Pathways of M. capsulatus

<p>Genomic information was used to predict the flow of carbon from methanotrophy pathways into carbon fixation pathways, and thence into glycolysis/gluconeogenesis and the TCA cycle. Locus names are indicated next to key steps. Some intermediates are omitted.</p