6 research outputs found

    Additional file 3: Figure S1. of Perilipin-2 modulates dietary fat-induced microbial global gene expression profiles in the mouse intestine

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    Principal component analysis for four data types (Taxa, Enzymes, Significant Differentially Expressed Transcripts and Metabolic Pathways). With each plot, p values (< 0.05) are provided indicating significant differences in clustering between each of the four pairwise comparisons. (PDF 912 kb

    Additional file 8: Figure S3. of Perilipin-2 modulates dietary fat-induced microbial global gene expression profiles in the mouse intestine

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    Comparison of glycolysis pathway enzyme expression between sample types. Three comparisons are shown: (A) Plin2-LF vs. WT-LF; (B) Plin2-HF vs. Plin2-LF; (C) WT-HF vs. WT-LF. Circular nodes indicate enzymes, with size indicating relative difference in expression between sample types and color indicating direction of change (see inset key). Associated heatmaps indicate global changes in expression for each enzyme, in addition to taxon-specific changes in expression for each of the 17 defined taxa colored according to phylum. (PDF 1138 kb

    Additional file 10: Figure S5. of Perilipin-2 modulates dietary fat-induced microbial global gene expression profiles in the mouse intestine

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    Diet-based comparisons of enzyme expression in pantothenate pathway. Two comparisons are shown: (A) Plin2-HF vs. Plin2-LF and (B) WT-HF vs. WT-LF. Circular nodes indicate enzymes, with size indicating relative difference in expression between sample types and color indicating direction of change (see inset key). Associated heatmaps indicate global changes in expression for each enzyme, in addition to taxon-specific changes in expression for each of the 17 defined taxa colored according to phylum. The following abbreviations are used: 5,6-dh-uracil (5,6-dihydro-uracil), N-cm-β-alanine (N-carbamoyl-β-alanine), N-pt-Cys (N-pantothenoyl-cysteine), and (R)-4′-P-pt-L-Cys ((R)-4′-phospho-pantothenoyl-l-cysteine. (PDF 1119 kb

    Additional file 14: Figure S8. of Perilipin-2 modulates dietary fat-induced microbial global gene expression profiles in the mouse intestine

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    Rarefaction analysis of annotated mRNA reads. Recovery of species (A) and enzymes (B) with increasing numbers of annotated mRNA reads (reads mapped to known transcripts) indicate that sequencing depth for each sample was sufficient to recover the vast majority of species and enzymes present within each of the 16 samples. Rarefaction analysis was performed using R. (PDF 16825 kb
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