Synergic deprotonation generates alkali-metal salts of tethered fluorenide NHC ligands co-complexed to alkali metal amides

Synergic combinations of alkali-metal hydrocarbyl/amide reagents were used to synthesise saturated N-heterocyclic carbene (NHC) ligands tethered to a fluorenide anion through deprotonation of a spirocyclic precursor, whereas conventional bases were not successful. The Li2 derivatives displayed a bridging amide between two Li atoms within the fluorenide-NHC pocket, whereas the Na2 and K2 analogues displayed extended solid-state structures with the fluorenide-NHC ligand chelating one alkali metal centre

Historical Acoustemology: Past, Present, and Future

This article surveys the field and methodology of historical acoustemology, an interdisciplinary area of study dedicated to understanding past sounds, hearers, and listeners in their historical contexts. The article charts the field’s emergence in the late 1990s and early 2000s, accounts for the field’s present trends (which center on the politics of listening subjectivity), and identifies future directions of inquiry. The article argues that historians should take account of a broader spectrum of past listeners, not just listening experts, and develop greater criticality about their own knowing-through-listening. The article makes the case for a future sound historical field grounded in the analysis of nonwritten sources, particularly sound archives and material culture, and argues that the use of new digital methods and the engagement of listening publics through a new public sound history should also become central to the work of the sound historian

Materialising contexts: virtual soundscapes for real-world exploration

© 2020, The Author(s). This article presents the results of a study based on a group of participants’ interactions with an experimental sound installation at the National Science and Media Museum in Bradford, UK. The installation used audio augmented reality to attach virtual sound sources to a vintage radio receiver from the museum’s collection, with a view to understanding the potentials of this technology for promoting exploration and engagement within museums and galleries. We employ a practice-based design ethnography, including a thematic analysis of our participants’ interactions with spatialised interactive audio, and present an identified sequence of interactional phases. We discuss how audio augmented artefacts can communicate and engage visitors beyond their traditional confines of line-of-sight, and how visitors can be drawn to engage further, beyond the realm of their original encounter. Finally, we provide evidence of how contextualised and embodied interactions, along with authentic audio reproduction, evoked personal memories associated with our museum artefact, and how this can promote interest in the acquisition of declarative knowledge. Additionally, through the adoption of a functional and theoretical aura-based model, we present ways in which this could be achieved, and, overall, we demonstrate a material object’s potential role as an interface for engaging users with, and contextualising, immaterial digital audio archival content

Constructing COMSOL Models of a Bacteriological Fuel Cell

We show very initial work on a specific bioelectrochemical system (BES), a bacteriologically driven 'fuel cell' (BFS), that is intended to process waste products, such as CO2 and brine. (1) Processing is the priority, not power generation (2) Really a Microbial Electrolysis Cell (MEC

Staging listening: new methods for engaging audiences with sound in museums

This article reports on the experimental methodology and key findings of the AHRC-funded impact and engagement project Sonic Futures: Collecting, Curating and Engaging with Sound at the National Science and Media Museum (2020–21). The project undertook a series of listening-based public engagement activities – described here as staging listening – to identify new ways of engaging listening audiences with sound technology objects in museums. These activities led to the creation of three new interactive sounding exhibit prototypes created jointly with audiences. Because the project took place during periods of lockdown caused by the coronavirus pandemic in the UK in 2020–21, the exhibit prototypes were created digitally and tested via online interaction. The article argues that engaging with listening audiences can diversify and enrich museum listening scenarios, a term we use here to describe auditory situations which elicit different kinds of listening attention, interaction and learning. These listening scenarios produce divergent signatures of listening, a concept we develop here to describe the various kinds of learning and engagement we observed throughout the project

Performance Evaluation of Staged Bosch Process for CO2 Reduction to Produce Life Support Consumables

Utilizing carbon dioxide to produce water and hence oxygen is critical for sustained manned missions in space, and to support both NASA's cabin Atmosphere Revitalization System (ARS) and In-Situ Resource Utilization (ISRU) concepts. For long term missions beyond low Earth orbit, where resupply is significantly more difficult and costly, open loop ARS, like Sabatier, consume inputs such as hydrogen. The Bosch process, on the other hand, has the potential to achieve complete loop closure and is hence a preferred choice. However, current single stage Bosch reactor designs suffer from a large recycle penalty due to slow reaction rates and the inherent limitation in approaching thermodynamic equilibrium. Developmental efforts are seeking to improve upon the efficiency (hence reducing the recycle penalty) of current single stage Bosch reactors which employ traditional steel wool catalysts. Precision Combustion, Inc. (PCI), with support from NASA, has investigated the potential for utilizing catalysts supported over short-contact time Microlith substrates for the Bosch reaction to achieve faster reaction rates, higher conversions, and a reduced recycle flows. Proof-of-concept testing was accomplished for a staged Bosch process by splitting the chemistry in two separate reactors, first being the reverse water-gas-shift (RWGS) and the second being the carbon formation reactor (CFR) via hydrogenation and/or Boudouard. This paper presents the results from this feasibility study at various operating conditions. Additionally, results from two 70 hour durability tests for the RWGS reactor are discussed

A Process-Based Ammonia Emission Model for Confinement Animal Feeding Operations—Model Development

A process-based modeling approach was used to develop a comprehensive and predictive ammonia emission model for estimating ammonia emission rates from animal feeding operations. The ammonia emission model consists of farm emission model (FEM) and animal allocation processor (AAP) and can be used to calculate ammonia emission rates both from an individual AFO and from a group of AFOs and also allows predictions of different time scale resolutions. The Farm Emission Model (FEM) covers five animal species, including dairy, beef cattle, swine, layers, broilers, and turkeys. For each species, the FEM reflects different farm practices with regards to animal feeding, animal housing, manure collection and storage, and land application. The overall structure and selected model components of FEM are described in this paper. Some computer simulation results for a finishing swine farm are presented. The predicted ammonia emission rates are variable during the day and over the period of the year

Insomnia prehabilitation in newly diagnosed breast cancer patients: Protocol for a pilot, multicentre, randomised controlled trial comparing nurse delivered sleep restriction therapy to sleep hygiene education (INVEST trial)

Introduction: Insomnia is a prevalent sleep disorder that negatively impacts daytime functioning and quality of life. Breast cancer patients report higher rates of insomnia and more circadian disruption than other cancer groups. Approximately 50% of patients experience acute insomnia following breast cancer diagnosis, which often persists during cancer treatment and rehabilitation. Sleep Restriction Therapy (SRT) is a clinically effective and tolerable treatment for persistent insomnia in breast cancer survivors. However, SRT has never been tested on patients with early signs of sleep disturbance who are undergoing cancer treatment. The aim of this pilot randomised controlled trial is to explore the feasibility and preliminary effectiveness of nurse delivered SRT for newly diagnosed breast cancer patients with acute insomnia. The trial has been registered on ClinicalTrials.gov (identifier: NCT06294041). Methods: The INVEST (INvestigating the Value of Early Sleep Therapy) trial will recruit 50 newly diagnosed breast cancer patients who meet criteria for acute insomnia. Patients will be recruited from breast cancer results clinics within two Scottish health boards (NHS Grampian and NHS Greater Glasgow and Clyde) and will be block randomised (1:1) to receive nurse delivered SRT or Sleep Hygiene Education (SHE). SRT will be delivered over 4 weekly sessions comprising two face-to-face meetings (either in person or online) and two telephone calls, whereas SHE will be administered in booklet form. Outcomes will be collected at baseline, 6 weeks, and 12 weeks post-randomisation. Primary outcomes in this trial relate to the feasibility of SRT for newly diagnosed breast cancer patients with acute insomnia. Specifically, we will explore (i) rates of patient recruitment and retention, (ii) intervention fidelity, (iii) data collection procedures and outcome measure completion, (iv) intervention acceptability. Secondary outcomes will focus on preliminary evaluation of patient responses to SRT, including insomnia severity, rest-activity rhythms, and mental health. Dissemination: Our dissemination plan comprises publishing trial outcomes in high-impact, peer-reviewed journals and on breast cancer charity websites and other patient resources. The outcomes from this pilot trial will also inform the development of a full-scale, multicentre RCT of SRT for acute insomnia in newly diagnosed breast cancer patients. University of Strathclyde is the sponsor (reference: UEC23/52). Protocol version v1.2 4 October 2023. Strengths and limitations of this study: This trial is the first to explore the value of sleep prehabilitation for newly diagnosed breast cancer patients. This will be the first trial to assess the feasibility of delivering SRT during breast cancer treatment, providing valuable insight into its tolerability and preliminary effectiveness. An embedded process evaluation will assess the acceptability of SRT, providing insight into potential optimisation of the intervention and recommendations for enhancing its future scalability and translation within cancer care. Due to the nature of the SRT intervention, nurse therapists and patients cannot be blinded to treatment allocation, increasing the risk of bias