5,888 research outputs found

    The analysis of sire buying policies

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    An expression is derived for the net present value of returns obtained through increased productivity of descendants of a purchased sire. This expression is useful for evaluating a given sire purchase, but is not so helpful in determining a sire buying policy. For this purpose, an analysis is made of the value of sire purchase from a breeding nucleus which is making constant genetic gains when the lag of the commercial population behind the nucleus has stabilised under a fixed policy. This leads to a criterion for deciding how long a sire should be used, which depends on price, breeding value, and rate of genetic gain in the nucleus. The optimum sire buying policy depends on the relation between price and breeding value of the sire. Competition for sires may change the relationship of price to breeding value so that no class of sire is the best buy if properly used and it is shown that in this case price is a quadratic function of breeding value. Prices paid by producers for boars auctioned from French performance test stations were found to be related to index value (I) by the approximate equation : price (francs) = 1 500 + 5(I- 100) + 0.5 (I- 100)2. For the observed price function the best policy is to buy boars with high (about 140) index value, and replace them after 15 months use. The net present value of an average boar is estimated as 2 000 francs.L’achat d’un gĂ©niteur sĂ©lectionnĂ© conduit Ă  des gains de productivitĂ© dans sa descendance. Une expression de la valeur nette actualisĂ©e des recettes qui en rĂ©sultent est Ă©tablie. Cette expression est utile pour juger de la valeur d’un achat donnĂ© mais elle n’est pas suffisante pour dĂ©terminer une politique gĂ©nĂ©rale d’achat de gĂ©niteurs. Dans ce but, une analyse est faite de la valeur d’un achat de mĂąle en provenance d’un noyau de sĂ©lection qui rĂ©alise des gains gĂ©nĂ©tiques constants quand le retard de la population commerciale sur le noyau s’est stabilisĂ© en fonction d’une politique donnĂ©e. Cela conduit Ă  un critĂšre pour dĂ©cider de la durĂ©e d’utilisation d’un mĂąle, qui dĂ©pend de son prix, de sa valeur gĂ©nĂ©tique et du progrĂšs gĂ©nĂ©tique dans le noyau. La politique d’achat optimale dĂ©pend de la relation entre le prix et la valeur gĂ©nĂ©tique du mĂąle. La concurrence entre les acheteurs peut modifier la relation entre le prix et la valeur gĂ©nĂ©tique, et aboutir Ă  une relation telle que tous les pĂšres ont la mĂȘme valeur nette actualisĂ©e Ă  condition qu’ils soient convenablement utilisĂ©s. Il est montrĂ© que, dans ce cas, le prix est une fonction de second degrĂ© de la valeur gĂ©nĂ©tique. Les prix payĂ©s par les producteurs pour les verrats vendus aux enchĂšres dans les stations françaises de contrĂŽle individuel sont liĂ©s Ă  la valeur de l’indice (I) par la relation approchĂ©e : prix (francs) = 1 500 + 5(I- 100) + 0.5 (I- 100)2. Pour une telle fonction, la meilleure politique, pour le producteur, consiste Ă  acheter des verrats Ă  haut indice (environ 140) et Ă  les remplacer aprĂšs une utilisation de 15 mois. La valeur nette actualisĂ©e d’un verrat moyen est estimĂ©e Ă  2 000 francs

    Optimal allocation of resources considering two sexes and selection in two stages

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    Optimal allocation of resources considering two sexes and selection in two stages

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    The distribution of limited testing resources between sexes and stages of selection was optimised for breeding structures employing one- or two-stage selection. The use of incomplete sampling was considered. Measurement expenditure generally favoured the sex subject to the highest selection intensity. Within a sex, the optimal intensity of measurement was dependent upon the proportion of available candidates required for breeding and on the level of available funding. It was optimal to test all of the available candidates when more than 40% was required for breeding. Single-stage selection was favoured when selection intensity was low and when the funding limit was high. The allocation of resources between stages of selection was complex. Results are expressed graphically for different relationships between measurement cost and selection accuracy, for a range of selection intensities in each sex, and for a range of funding limitations. The methods are applicable to any livestock industry where multi-stage selection is utilised and where a relationship between measurement cost and accuracy can be ascertained. A numerical illustration pertinent to a wool sheep breeding scheme is examined

    Genetic interaction between sire and population of mates in Drosophila melanogaster

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    Efficacy of personalized cognitive counseling in men of color who have sex with men: secondary data analysis from a controlled intervention trial.

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    In a previous report, we demonstrated the efficacy of a cognitively based counseling intervention compared to standard counseling at reducing episodes of unprotected anal intercourse (UAI) among men who have sex with men (MSM) seeking HIV testing. Given the limited number of efficacious prevention interventions for MSM of color (MOC) available, we analyzed the data stratified into MOC and whites. The sample included 196 white MSM and 109 MOC (23 African Americans, 36 Latinos, 22 Asians, eight Alaskan Natives/Native Americans/Hawaiian/Pacific Islander, and 20 of mixed or other unspecified race). Among MOC in the intervention group, the mean number of episodes of UAI declined from 5.1 to 1.6 at six months and was stable at 12 months (1.8). Among the MOC receiving standard counseling, the mean number of UAI episodes was 4.2 at baseline, 3.9 at six months and 2.1 at 12 months. There was a significant treatment effect overall (relative risk 0.59, 95% confidence interval 0.35-0.998). These results suggest that the intervention is effective in MOC
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