Adjusted incident rate ratios (IRR) and 95% confidence intervals (CI) for recurrent admissions for respiratory sub-conditions for sub cohorts defined by TBSA burn severity versus uninjured cohort.

<p>Adjusted incident rate ratios (IRR) and 95% confidence intervals (CI) for recurrent admissions for respiratory sub-conditions for sub cohorts defined by TBSA burn severity versus uninjured cohort.</p

Baseline demographics, pre-existing health status factors and study outcomes for the burn cohort vs. uninjured cohort.

<p>Baseline demographics, pre-existing health status factors and study outcomes for the burn cohort vs. uninjured cohort.</p

Reduced CD8 and increased NK/NKT response to viral infection in the airway draining lymph nodes after burn injury.

<p>At day 4 and day 10 post-infection no significant difference was observed in total cell number of CD3, CD4 and CD8 cell numbers (a-d). CD4 proliferation (Ki67+), antigen experience (CD44+), activation (CD25+) and CD4 Treg frequency were all not significantly different between burn and sham treatment groups (e-h). CD8 proliferation appeared to be reduced after burn injury (p = 0.056, i) with a loss of the significant increase in CD8 cells during infection compared to naïve mice seen in sham injured animals (l), but no other changes in the CD8 profile were observed (j-k). NK and NKT cell number appear to be increased at day 4 and day 10 post-infection respectively in the burn injury group (m, n, p = 0.091, p = 0.061). Gran B positive NK and NKT cells were both significantly elevated at day 4 post-infection in the burn injury group (o, p). * p<0.05.</p