Additional file 15: of Proteogenomic analysis of psoriasis reveals discordant and concordant changes in mRNA and protein abundance

Fatty acid binding protein 5 (FABP5) and serpin peptidase inhibitor 4 (SERPINB4) show correspondent increases in mRNA and protein abundance in psoriasis lesions. (A) Expression of FABP5 in lesional (PP), uninvolved (PN) and normal skin from healthy controls (NN) (RT-PCR; n = 8 per group). (B) FABP5 immunohistochemistry staining in PP skin. (C) FABP5 immunohistochemistry staining in PN skin. (D) Expression of SERPINB4 in lesional (PP), uninvolved (PN) and normal skin from healthy controls (NN) (RT-PCR; n = 8 per group). For RT-PCR analyses (A and D), two sets of fold-changes and p values are listed (top: PP versus PN; bottom: PP versus NN). Gene expression for each sample is normalized to glyceraldehyde-3-phosphate dehydrogenase (GAPDH). (TIFF 4624 kb