Relative combined effect of NHV and recovery over time (a) and individual effects of NHV-E and NHV-L and recovery over time (b).

<p>Relative combined effect of NHV and recovery over time (a) and individual effects of NHV-E and NHV-L and recovery over time (b).</p

Marginal predictions of Barthel Index mean scores for the NHV study groups at time points based on the three-level Tobit model.

<p>Marginal predictions of Barthel Index mean scores for the NHV study groups at time points based on the three-level Tobit model.</p

NHV program components and rehabilitation services.

<p>NHV program components and rehabilitation services.</p

Subject flow in the NHV effectiveness study.

<p>Subject flow in the NHV effectiveness study.</p

Ceiling effect of the Barthel Index in amputees (three patients from the control group and one from NHV-L begin with a censored score at baseline).

<p>Observations for one patient at different time points are connected by lines.</p

Baseline characteristics of the NHV study groups.

<p>SD = Standard Deviation; BI = Barthel Index. ^‡F–test for metric; Chi–square for categorical variables. *Significant difference between NHV-E and Controls only, according to post hoc tests (Scheffé), ^†T-test.</p

Sensitivity analysis: estimated change in NHV rehabilitation effect based on different dropout imputation scenarios.

<p>Legend: Scenario A  =  no dropouts incurred any change in Barthel Index; Scenario B  =  all dropouts decreased by ten points in Barthel Index at follow up; Scenario C  =  dropouts from the intervention groups did not change between baseline and follow up, while dropouts from the control group increased by ten points in Barthel Index; Complete cases  =  model estimation with valid cases only (see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0053995#pone-0053995-t002" target="_blank">Table 2</a>). Error bars represent 95% confidence intervals.</p

Parameter estimates for Barthel Index (BI) based on the three-level Tobit model.

<p>Log Likelihood: −3415.094; Bayesian Information Criterion (BIC): 6947.956.</p><p>SE = standard error, z = standardized coefficient; EQ = earthquake; MP = point of measurement; cov = covariance *p<0.05, **p<0.01, *** p<0.001.</p