1,421 research outputs found

    Association between depression and concurrent Type 2 diabetes outcomes varies by diabetes regimen

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    Aims  Although depression has weak associations with several Type 2 diabetes mellitus (DM) outcomes, it is possible that these associations are concentrated within certain patient subgroups that are more vulnerable to their effects. This study tested the hypothesis that depression is related to glycaemic control and diabetes-related quality of life (DQOL) in patients who are prescribed injected insulin, but not those on oral glucose-lowering agents alone. Methods  Participants (103 on insulin, 155 on oral glucose-lowering agents alone) with Type 2 DM were recruited from a large US healthcare system and underwent assessment of glycaemic control (glycated haemoglobin; HbA 1c ), medication adherence and diabetes self-care behaviours, DQOL and depression (none, mild, moderate/severe). Results  There was a significant regimen × depression interaction on HbA 1c ( P  = 0.002), such that depression was associated with HbA 1c in patients using insulin (β = 0.35, P  < 0.001) but not in patients using oral agents alone (β = –0.08, P  = NS). There was a similar interaction when quality of life was analysed as an outcome ( P  = 0.002). Neither effect was mediated by regimen adherence. Conclusions  The generally weak association between depression and glycaemic control is concentrated among patients who are prescribed insulin. Similarly, the association between depression and illness quality of life is strongest in patients prescribed insulin. Because this is not attributable to depression-related adherence problems, psychophysiological mechanisms unique to this group ought to be carefully investigated. Clinicians might be especially vigilant for depression in Type 2 DM patients who use insulin and consider its potential impact upon their illness course. Diabet. Med. 25, 1324–1329 (2008)Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/73538/1/j.1464-5491.2008.02590.x.pd

    Diversification as a Strategy: A Research-Based Plan for Arts Organizations to Cultivate New Audiences

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    Building a more inclusive audience is not a far-fetched idea; system diversification by its very nature is a performance strategy, not a performance goal. Changing audience demographics requires well laid out plans, achievable goals, effective processes, and a total organizational commitment to diversification. This report was created to provide perspectives that inform executive leaders in arts organizations who plan to attract diverse audiences. It highlights nine research-based recommendations for audience diversification. The report is unique in that it layers four approaches that, if used simultaneously, have the potential to both increase the likelihood of success and decrease the amount of time it will take to achieve results by framing audience diversification as a strategy, not a goal

    Diversification as a Strategy: A Research-Based Plan to Cultivate New Audiences at the Richmond Symphony

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    Building a more inclusive audience is not a far-fetched idea; system diversification by its very nature is a performance strategy, not a performance goal. Changing audience demographics requires well laid out plans, achievable goals, effective processes, and a total organizational commitment to diversification. This report was created to provide perspectives that inform executive leaders in arts organizations who plan to attract diverse audiences. It highlights nine research-based recommendations for audience diversification. Our report is unique in that it layers four approaches that, if used simultaneously, have the potential to both increase the likelihood of success and decrease the amount of time it will take to achieve results by framing audience diversification as a strategy, not a goal

    Toward quantification of the feasible potential of land-based carbon dioxide removal

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    Global climate-change overshoot scenarios, where warming exceeds Paris Agreement limits before being brought back down, are highly dependent on land-based carbon dioxide removal (CDR). In the Intergovernmental Panel on Climate Change (IPCC) Sixth Assessment Report (AR6), such scenarios are supported by optimistic global assessments of the technical and economic potential for land-based CDR. However, a further type of potential—the ‘‘feasible’’ potential, which includes socio-cultural, environmental, and institutional factors—is noted in the AR6 but not quantified. Here, we set out research frameworks to work toward quantification of this feasible potential. We first argue that quantifying the feasible potential will substantiallyreduce current assessed CDR potential. Second, we demonstrate how transdisciplinary methods are improving understanding of feasibility constraints on land-based CDR. Third, we explore frameworks for synthesizing these advances during the next IPCC assessment process. We conclude that the research community should carefully consider the use of techno-economic CDR assessments in evidence for policymaker

    A global behavioural model of human fire use and management: WHAM! v1.0

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    Fire is an integral ecosystem process and a major natural source of vegetation disturbance globally. Yet at the same time, humans use and manage fire in diverse ways and for a huge range of purposes. Therefore, it is perhaps unsurprising that a central finding of the first Fire Model Intercomparison Project was simplistic representation of humans is a substantial shortcoming in the fire modules of dynamic global vegetation models (DGVMs). In response to this challenge, we present a novel, global geospatial model that seeks to capture the diversity of human–fire interactions. Empirically grounded with a global database of anthropogenic fire impacts, WHAM! (the Wildfire Human Agency Model) represents the underlying behavioural and land system drivers of human approaches to fire management and their impact on fire regimes. WHAM! is designed to be coupled with DGVMs (JULES-INFERNO in the current instance), such that human and biophysical drivers of fire on Earth, and their interactions, can be captured in process-based models for the first time. Initial outputs from WHAM! presented here are in line with previous evidence suggesting managed anthropogenic fire use is decreasing globally and point to land use intensification as the underlying reason for this phenomenon.</p

    Community‐Based Interdisciplinary Research: Introduction to the Special Issue

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    This special issue on community‐based interdisciplinary research grew out of the work of the SCRA Interdisciplinary Task Force and an Interdisciplinary Working Conference held at Vanderbilt University in May, 2004. In this introduction to the special issue, the historical context for interdisciplinary underpinnings for community psychology theory, research, action and training is first depicted. This is followed by a brief description of the mission and work of the recent SCRA Interdisciplinary Task Force and the Interdisciplinary Working Conference. The introduction concludes with a brief summary of the papers in the two main sections of the special issue, Prospects and Perspectives (four scholarly papers and three commentaries) and Community‐Based Interdisciplinary Action‐Research (four interdisciplinary action‐research projects).Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/117166/1/ajcp9063.pd
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