Mrk 1419 - a new distance determination

Water vapor megamasers from the center of active galaxies provide a powerful tool to trace accretion disks at sub-parsec resolution and, through an entirely geometrical method, measure direct distances to galaxies up to 200 Mpc. The Megamaser Cosmology Project (MCP) is formed by a team of astronomers with the aim of identifying new maser systems, and mapping their emission at high angular resolution to determine their distance. Two types of observations are necessary to measure a distance: single-dish monitoring to measure the acceleration of gas in the disk, and sensitive VLBI imaging to measure the angular size of the disk, measure the rotation curve, and model radial displacement of the maser feature. The ultimate goal of the MCP is to make a precise measurement of H0 by measuring such distances to at least 10 maser galaxies in the Hubble flow. We present here the preliminary results from a new maser system, Mrk 1419. Through a model of the rotation from the systemic masers assuming a narrow ring, and combining these results with the acceleration measurement from the Green Bank Telescope, we determine a distance to Mrk 1419 of 81\pm10 Mpc. Given that the disk shows a significant warp that may not be entirely traced by our current observations, more sensitive observations and more sophisticated disk modeling will be essential to improve our distance estimation to this galaxy.Comment: 5 pages, 3 figures, to appear in the proceedings of IAU Symposium 287 "Cosmic Masers- from OH to Ho", in Stellenbosch, S

Towards Precision Supermassive Black Hole Masses using Megamaser Disks

Megamaser disks provide the most precise and accurate extragalactic supermassive black hole masses. Here we describe a search for megamasers in nearby galaxies using the Green Bank Telescope (GBT). We focus on galaxies where we believe that we can resolve the gravitational sphere of influence of the black hole and derive a stellar or gas dynamical measurement with optical or NIR observations. Since there are only a handful of super massive black holes (SMBH) that have direct black hole mass measurements from more than one method, even a single galaxy with a megamaser disk and a stellar dynamical black hole mass would provide necessary checks on the stellar dynamical methods. We targeted 87 objects from the Hobby-Eberly Telescope Massive Galaxy Survey, and detected no new maser disks. Most of the targeted objects are elliptical galaxies with typical stellar velocity dispersions of 250 km/s and distances within 130 Mpc. We discuss the implications of our non-detections, whether they imply a threshold X-ray luminosity required for masing, or possibly reflect the difficulty of maintaining a masing disk around much more massive (>10^8 Msun) black holes at low Eddington ratio. Given the power of maser disks at probing black hole accretion and demographics, we suggest that future maser searches should endeavour to remove remaining sample biases, in order to sort out the importance of these covariant effects.Comment: 9 pages, 5 figures, Apj, updated to match the accepted versio

Refining the M_BH-V_c scaling relation with HI rotation curves of water megamaser galaxies

Black hole - galaxy scaling relations provide information about the coevolution of supermassive black holes and their host galaxies. We compare the black hole mass - circular velocity (MBH - Vc) relation with the black hole mass - bulge stellar velocity dispersion (MBH - sigma) relation, to see whether the scaling relations can passively emerge from a large number of mergers, or require a physical mechanism, such as feedback from an active nucleus. We present VLA H I observations of five galaxies, including three water megamaser galaxies, to measure the circular velocity. Using twenty-two galaxies with dynamical MBH measurements and Vc measurements extending to large radius, our best-fit MBH - Vc relation, log MBH = alpha + beta log(Vc /200 km s^-1), yields alpha = 7.43+/-0.13, beta = 3.68+1.23/-1.20, and intrinsic scatter epsilon_int = 0.51+0.11/-0.09. The intrinsic scatter may well be higher than 0.51, as we take great care to ascribe conservatively large observational errors. We find comparable scatter in the MBH - sigma relations, epsilon_int = 0.48+0.10/-0.08, while pure merging scenarios would likely result in a tighter scaling with the dark halo (as traced by Vc) than baryonic (sigma) properties. Instead, feedback from the active nucleus may act on bulge scales to tighten the MBH - sigma relation with respect to the MBH - Vc relation, as observed.Comment: 27 pages, 15 figures, ApJ accepte

On the origin of non-monotonic doping dependence of the in-plane resistivity anisotropy in Ba(Fe1−xTx_{1-x}T_x)2_2As2_2, TT = Co, Ni and Cu

The in-plane resistivity anisotropy has been measured for detwinned single crystals of Ba(Fe$_{1-x}$Ni$_x$)$_2$As$_2$ and Ba(Fe$_{1-x}$Cu$_x$)$_2$As$_2$. The data reveal a non-monotonic doping dependence, similar to previous observations for Ba(Fe$_{1-x}$Co$_x$)$_2$As$_2$. Magnetotransport measurements of the parent compound reveal a non-linear Hall coefficient and a strong linear term in the transverse magnetoresistance. Both effects are rapidly suppressed with chemical substitution over a similar compositional range as the onset of the large in-plane resistivity anisotropy. It is suggested that the relatively small in-plane anisotropy of the parent compound in the spin density wave state is due to the presence of an isotropic, high mobility pocket of reconstructed Fermi surface. Progressive suppression of the contribution to the conductivity arising from this isotropic pocket with chemical substitution eventually reveals the underlying in-plane anisotropy associated with the remaining FS pockets.Comment: 12 pages, 9 figure

Using Megamaser Disks to Probe Black Hole Accretion

We examine the alignment between H_2O megamaser disks on sub-pc scales with circumnuclear disks and bars on <500 pc scales observed with HST/WFC3. The HST imaging reveals young stars, indicating the presence of gas. The megamaser disks are not well aligned with the circumnuclear bars or disks as traced by stars in the HST images. We speculate on the implications of the observed misalignments for fueling supermassive black holes in gas-rich spiral galaxies. In contrast, we find a strong preference for the rotation axes of the megamaser disks to align with radio continuum jets observed on >50 pc scales, in those galaxies for which radio continuum detections are available. Sub-arcsecond observations of molecular gas with ALMA will enable a more complete understanding of the interplay between circumnuclear structures.Comment: Error in Figure 4 corrected, references added. 7 pages, 4 figures, to be published in the Astrophysical Journa

Synthetic genome recoding: new genetic codes for new features.

Full genome recoding, or rewriting codon meaning, through chemical synthesis of entire bacterial chromosomes has become feasible in the past several years. Recoding an organism can impart new properties including non-natural amino acid incorporation, virus resistance, and biocontainment. The estimated cost of construction that includes DNA synthesis, assembly by recombination, and troubleshooting, is now comparable to costs of early stage development of drugs or other high-tech products. Here, we discuss several recently published assembly methods and provide some thoughts on the future, including how synthetic efforts might benefit from the analysis of natural recoding processes and organisms that use alternative genetic codes

A Dynamic Knowledge Management Framework for the High Value Manufacturing Industry

Dynamic Knowledge Management (KM) is a combination of cultural and technological factors, including the cultural factors of people and their motivations, technological factors of content and infrastructure and, where these both come together, interface factors. In this paper a Dynamic KM framework is described in the context of employees being motivated to create profit for their company through product development in high value manufacturing. It is reported how the framework was discussed during a meeting of the collaborating company’s (BAE Systems) project stakeholders. Participants agreed the framework would have most benefit at the start of the product lifecycle before key decisions were made. The framework has been designed to support organisational learning and to reward employees that improve the position of the company in the market place

Ankyrin binding mediates L1CAM interactions with static components of the cytoskeleton and inhibits retrograde movement of L1CAM on the cell surface

The function of adhesion receptors in both cell adhesion and migration depends critically on interactions with the cytoskeleton. During cell adhesion, cytoskeletal interactions stabilize receptors to strengthen adhesive contacts. In contrast, during cell migration, adhesion proteins are believed to interact with dynamic components of the cytoskeleton, permitting the transmission of traction forces through the receptor to the extracellular environment. The L1 cell adhesion molecule (L1CAM), a member of the Ig superfamily, plays a crucial role in both the migration of neuronal growth cones and the static adhesion between neighboring axons. To understand the basis of L1CAM function in adhesion and migration, we quantified directly the diffusion characteristics of L1CAM on the upper surface of ND-7 neuroblastoma hybrid cells as an indication of receptor–cytoskeleton interactions. We find that cell surface L1CAM engages in diffusion, retrograde movement, and stationary behavior, consistent with interactions between L1CAM and two populations of cytoskeleton proteins. We provide evidence that the cytoskeletal adaptor protein ankyrin mediates stationary behavior while inhibiting the actin-dependent retrograde movement of L1CAM. Moreover, inhibitors of L1CAM–ankyrin interactions promote L1CAM-mediated axon growth. Together, these results suggest that ankyrin binding plays a crucial role in the anti-coordinate regulation of L1CAM-mediated adhesion and migration

Implications of New Gallex Results for the MSW Solution of the Solar Neutrino Problem

We compare the implications for 7Be and pp neutrinos of the two MSW fits to the new GALLEX solar neutrino measurements . Small mixing angle solutions tend to suppress the former as electron-neutrinos, but not the latter, and large angle solutions tend to reduce both by about a factor of 2. The consequences for BOREXINO and similar solar neutrino--electron scattering experiments are discussed.Comment: 7 pages (plus 3 figures available upon request) UTAPHY-HEP-