Scatterplot of AEA vs. RPS for all questions, with the top 10 by RPS shown in red.

<p>Scatterplot of AEA vs. RPS for all questions, with the top 10 by RPS shown in red.</p

Top ten questions ranked by RPS.

<p>Top ten questions ranked by RPS.</p

Kaplan-Meier plot of survival time of children with SAM admitted with and without diarrhoea.

<p>Kaplan-Meier plot of survival time of children with SAM admitted with and without diarrhoea.</p

Blood culture isolates in children admitted with diarrhoea.

<p>Blood culture isolates in children admitted with diarrhoea.</p

Multivariable logistic regression variables associated with death in children with severe malnutrition and diarrhoea at admission.

<p>Different models with and without low MUAC were tested because MUAC has been reported to vary with hydration status.</p

Clinical and laboratory features by mortality of 592 children admitted with diarrhoea.

<p>Clinical and laboratory features by mortality of 592 children admitted with diarrhoea.</p

Frequency of baseline clinical features in 1206 severely malnourished children.

<p> <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0038321#pone-0038321-t001" target="_blank"><b>Tables 1</b></a><b> and </b><a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0038321#pone-0038321-t002" target="_blank"><b>2</b></a><b> legend.</b></p>a<p>APLS definition.</p>b<p>Impaired consciousness  =  prostration or coma.</p>c<p>WHO definition of shock  =  impaired consciousness <i>plus</i> weak pulse volume <i>plus</i> CRT>3 seconds.</p>d<p>WHO features of severe dehydration  = 2 or more of (sunken eyes or decreased skin turgour or lethargy or inability to drink).</p>e<p>WHO Danger signs  =  Hypothermia or hypoglycaemia or lethargy.</p

Estimated change (beta coefficients) in frequencies of memory B-cell subsets with variations in age, HIV status, proportions of memory T_FH cells, viremia and HAART in multivariable regression.

<p>Estimated change (beta coefficients) in frequencies of memory B-cell subsets with variations in age, HIV status, proportions of memory T_FH cells, viremia and HAART in multivariable regression.</p

In the HIV-infected cohort, proportions of total follicular-homing CD4 T cells are directly correlated with CD4 percentages.

<p>Correlation analyses between CD4 T cells (as percentage of total lymphocytes) and: (A) total follicular-homing CD4 T cells (CXCR5⁺CD4⁺), (B) memory follicular-homing CD4 T cells (CXCR5⁺CD45RO⁺CD4⁺), (C) memory T_FH cells (CXCR5⁺CD45RO⁺PD1⁺CD4⁺), (D) central memory follicular-homing CD4 T cells (CXCR5⁺CD45RO⁺CCR7⁺CD4⁺), (E) effector memory follicular-homing CD4 T cells (CXCR5⁺CD45RO⁺CCR7^-CD4⁺), (F) central memory T_FH cells (CXCR5⁺CD45RO⁺PD1⁺CCR7⁺CD4⁺) and (G) effector memory T_FH cells (CXCR5⁺CD45RO⁺PD1⁺CCR7^-CD4⁺). Circles represent highly viremic children and squares represent lowly viremic children. Red symbols represent HAART-naïve children and blue symbols represent HAART-treated children. Statistical test: Spearman’s rank-order correlation.</p

Characteristics of the study population.

<p>Characteristics of the study population.</p