Methyldibromoglutaronitrile is an important contact allergen in The Netherlands

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[Nickel allergy and orthodontics]

Contains fulltext : 79765.pdf (publisher's version ) (Closed access)Nickel hypersensitivity is a common problem, especially among young females, with a prevalence of 5 to 10%, increasing to 30%. In comparison with the oral mucosa, skin is more sensitive to an allergic reaction. The oral mucosa is less sensitive to nickel due to the difference in anatomical structure and the presence of pellicle. Nickel is used in many orthodontic appliances. Due to corrosion nickel ions can be released into the oral cavity. The extent of the corrosion of the appliance depends on the pH, the composition of saliva and plaque, temperature and mechanical loading. In spite of the relatively high amount of nickel processed in orthodontic appliances nickel allergies are rare. In cases of nickel-hypersensitivity, nickel-free appliances should be used

Methyldibromoglutaronitrile is an important contact allergen in The Netherlands

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Routine patch testing with fragrance chemicals in The Netherlands

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