Investigating prevalence of Helicobacter pylori and histological changes in patients with dyspepsia in Khorramabad City during 2013-2015

Dyspepsia which is a digestive syndrome with a prevalence of 50 in some areas can be an important factor in Helicobacter pylori infection syndrome. This study was aimed to evaluate relative frequency of Helicobacter pylori infection and histological changes in dyspeptic patients presented to the Endoscopic unit of Shahid Rahimi and Shohadaye Ashayer hospitals in Khorramabad city, Iran. In this cross-sectional study, the population included all patients with dyspepsia referred to Endoscopic Unit of Shahid Rahimi and Shohadaye Ashayer hospitals in Khorramabad during the period of 2013-2015. After performing endoscopy, H. pylori diagnosis was done by biopsy method. In this study, 5213 patients with dyspepsia (including 49.2 male and 50.8 female) with the age range of 12 to 90 years (mean 17.36 +/- 48.24 years) were studied. From this population, 57.3 percent were infected with Helicobacter pylori (50.8 of men and 49.2 women). Most positive cases were over 60 years old and the most histological changes were respectively chronic active gastritis (40.3). Similar to other studies, the prevalence of Helicobacter pylori infection is average in the population; however, these rates might be reduced through increased awareness and health care