2,234 research outputs found
Quantitative and empirical demonstration of the Matthew effect in a study of career longevity
The Matthew effect refers to the adage written some two-thousand years ago in
the Gospel of St. Matthew: "For to all those who have, more will be given."
Even two millennia later, this idiom is used by sociologists to qualitatively
describe the dynamics of individual progress and the interplay between status
and reward. Quantitative studies of professional careers are traditionally
limited by the difficulty in measuring progress and the lack of data on
individual careers. However, in some professions, there are well-defined
metrics that quantify career longevity, success, and prowess, which together
contribute to the overall success rating for an individual employee. Here we
demonstrate testable evidence of the age-old Matthew "rich get richer" effect,
wherein the longevity and past success of an individual lead to a cumulative
advantage in further developing his/her career. We develop an exactly solvable
stochastic career progress model that quantitatively incorporates the Matthew
effect, and validate our model predictions for several competitive professions.
We test our model on the careers of 400,000 scientists using data from six
high-impact journals, and further confirm our findings by testing the model on
the careers of more than 20,000 athletes in four sports leagues. Our model
highlights the importance of early career development, showing that many
careers are stunted by the relative disadvantage associated with inexperience.Comment: 13 pages, 7 figures, 4 Tables; Revisions in response to critique and
suggestions of referee
Growth of ultra-uniform graphene using a Ni/W bilayer metal catalyst
We investigated a bilayer catalyst system consisting of polycrystalline Ni and W films for growing mono-layer graphene over large areas. Highly uniform graphene was grown on Ni/W bilayer film with 100% coverage. The graphene grown on Ni/W bilayer film and transferred onto an insulating substrate exhibited average hole and electron mobilities of 727 and 340 cm(2)V(-1)s(-1), respectively. A probable growth mechanism is proposed based on X-ray diffractometry and transmission electron microscopy, which suggests that the reaction between diffused carbon and tungsten atoms results in formation of tungsten carbides. This reaction allows the control of carbon precipitation and prevents the growth of non-uniform multilayer graphene on the Ni surface; this has not been straightforwardly achieved before. These results could be of importance in better understanding mono-layer graphene growth, and suggest a facile fabrication route for electronic applications. (C) 2015 AIP Publishing LLCopen0
Information flow between composite stock index and individual stocks
We investigate the strength and the direction of information transfer in the
U.S. stock market between the composite stock price index of stock market and
prices of individual stocks using the transfer entropy. Through the
directionality of the information transfer, we find that individual stocks are
influenced by the index of the market.Comment: 8 pages, 4 figure
A RUNX2 stabilization pathway mediates physiologic and pathologic bone formation
The osteoblast differentiation capacity of skeletal stem cells (SSCs) must be tightly regulated, as inadequate bone formation results in low bone mass and skeletal fragility, and over-exuberant osteogenesis results in heterotopic ossification (HO) of soft tissues. RUNX2 is essential for tuning this balance, but the mechanisms of posttranslational control of RUNX2 remain to be fully elucidated. Here, we identify that a CK2/HAUSP pathway is a key regulator of RUNX2 stability, as Casein kinase 2 (CK2) phosphorylates RUNX2, recruiting the deubiquitinase herpesvirus-associated ubiquitin-specific protease (HAUSP), which stabilizes RUNX2 by diverting it away from ubiquitin-dependent proteasomal degradation. This pathway is important for both the commitment of SSCs to osteoprogenitors and their subsequent maturation. This CK2/HAUSP/RUNX2 pathway is also necessary for HO, as its inhibition blocked HO in multiple models. Collectively, active deubiquitination of RUNX2 is required for bone formation and this CK2/HAUSP deubiquitination pathway offers therapeutic opportunities for disorders of inappropriate mineralization
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