2,118 research outputs found

    Portraying China as an alternative to U. S. Hegemony: The China daily’s framing of the arab spring

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    © 2019, © 2019 Taylor & Francis Group, LLC. This study explored how China’s most authoritative English news medium, The China Daily, portrayed the Arab Spring within the context of the concerns of the Chinese government about the possibility of social movements within its own territory. It found that The China Daily utilized several characteristics–story framing, reliance on official sources, and delegitimization–of the “protest paradigm” to degrade the significance of the Arab Spring. By making the voices of China’s political and economic elites the most visible in its news stories, this paper advocated the Chinese government’s perspectives on the Arab Spring, while minimalizing those of Arab citizens and social activists. More significantly, it tried to present the Arab Spring as an issue that might serve to revitalize the patriotism of the Chinese people. The paper’s coverage laid emphasis on the increasing global power and influence of China in the Middle East and, at the same time, encouraged the Chinese people’s support for their own government

    Coil-assisted retrograde transvenous obliteration for the treatment of duodenal varix

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    Duodenal variceal bleeding is a rare but potentially life-threatening complication of portal hypertension. Endoscopic therapy is usually the initial treatment option for bleeding duodenal varices, but it is not always feasible or successful. We present a technique of coil-assisted retrograde transvenous obliteration in a patient with duodenal varices originating from the inferior pancreaticoduodenal vein and draining into the right ovarian vein

    MAP1981c, a Putative Nucleic Acid-Binding Protein, Produced by Mycobacterium avium subsp. paratuberculosis, Induces Maturation of Dendritic Cells and Th1-Polarization

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    Mycobacterium avium subsp. paratuberculosis (MAP) is the causative pathogen of chronic granulomatous enteropathy (Johne's disease) in animals, and has been focused on its association with various autoimmune diseases in humans, including Crohn's disease. The discovery of novel mycobacterial antigens and exploring their role in host immunity can contribute to the advancement of effective defense strategies including vaccines and diagnostic tools. In a preliminary study, we identified cellular extract proteins of MAP that strongly react with the blood of patients with Crohn's disease. In particular, MAP1981c, a putative nucleic acid-binding protein, showed high expression levels and strong reactivity to IgG and IgM in the sera of patients. Here, we investigated the immunological features of MAP1981c and focused on its interaction with dendritic cells (DCs), confirming its immunomodulatory ability. MAP1981c was shown to recognize Toll-like receptor (TLR) 4, and induce DC maturation and activation by increasing the expression of co-stimulatory (CD80 and CD86) and MHC class I/II molecules and the secretion of pro-inflammatory cytokines (IL-6, IL-1β, and TNF-α) in DCs. This DC activation by MAP1981c was mediated by downstream signaling of TLR4 via MyD88- and TRIF-, MAP kinase-, and NF-κB-dependent signaling pathways. In addition, MAP1981c-treated DCs activated naïve T cells and induced the differentiation of CD4+ and CD8+ T cells to express T-bet, IFN-γ, and/or IL-2, but not GATA-3 and IL-4, thus indicating that MAP1981c contributes to Th1-type immune responses both in vitro and in vivo. Taken together, these results suggest that MAP1981c is a novel immunocompetent antigen that induces DC maturation and a Th1-biased response upon DC activation, suggesting that MAP1981c can be an effective vaccine and diagnostic target

    Issue Salience in the U.S. Elections: “Partisan Domestication” between South Korean Newspapers

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    This study examines how two newspapers in South Korea, one conservative and one liberal, covered the U.S. presidential election of 2008. The study found that there was a significant divergence in the emphasis placed on certain types of issues between the two ideologically polarized newspapers. While the liberal Hankyoreh Daily placed more emphasis on social justice issues –such as racial equality and the abolition of social discrimination, the conservative Chosun Daily highlighted “human interest” issues, focusing on more trivial topics such as the candidates’ gender, family, and fashion preferences. There was also a difference in the types of news sources used by the two newspapers. The Hankyoreh Daily sought to represent the voices of the South Korean elite, while The Chosun Daily used American politicians as one of its major source of information. This study argues that a news organization’s ideological orientation is an important factor, which influences South Korean newspapers’ “domestication” of the U.S. election, which was staged in a distant region

    GAIT ASYMMETRY IN CHILDREN WITH DOWN SYNDROME

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    It has been reported that approximately 80% of children with Down syndrome (OS) exhibit gait problems (Matteo, 2002), characterized by flat-footed contact with no heel-strike, excessive abduction of the leg in the swing phase, and abnormal knee and hip f1exions throughout the gait cycle (Parker et aI., 1986). Due to muscle hypotonia, muscle weakness, !igamentous laXity, and other orthopedic abnormalities, different gait characteristics exist. The purpose of this study was to investigate the gait (walking and running) asymmetry in children with OS

    Effects of a dielectric barrier discharge (DBD) on characteristics of polyaniline nanoparticles synthesized by a solution plasma process with an Ar gas bubble channel

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    The quality of polyaniline nanoparticles (PANI NPs) synthesized in plasma polymerization depends on the discharge characteristics of a solution plasma process (SPP). In this paper, the low temperature dielectric barrier discharge (DBD) is introduced to minimize the destruction of aniline molecules induced by the direct current (DC) spark discharge. By adopting the new electrode structure coupled with a gas channel, a low temperature DBD is successfully implemented in a SPP, for the first time, thus inducing an effective interaction between the Ar plasma and aniline monomer. We examine the effects of a low temperature DBD on characteristics of polyaniline nanoparticles synthesized by a SPP with an Ar gas bubble channel. As a result, both carbonization of aniline monomer and erosion of the electrode are significantly reduced, which is confirmed by analyses of the synthesized PANI NPs. © 2020 by the authors.1

    A Herbal Medicine, Gongjindan

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    This study protocol aims to explore the effectiveness, safety, and cost-effectiveness of a herbal medication, Gongjindan (GJD), in patients with chronic dizziness. This will be a prospective, multicenter, randomized, double-blind, placebo-controlled, parallel-group, clinical trial. Seventy-eight patients diagnosed with Meniere’s disease, psychogenic dizziness, or dizziness of unknown cause will be randomized and allocated to either a GJD or a placebo group in a 1 : 1 ratio. Participants will be orally given 3.75 g GJD or placebo in pill form once a day for 56 days. The primary outcome measure will be the Dizziness Handicap Inventory score. Secondary outcome measures will be as follows: severity (mean vertigo scale and visual analogue scale) and frequency of dizziness, balance function (Berg Balance Scale), fatigue (Fatigue Severity Scale) and deficiency pattern/syndrome (qi blood yin yang-deficiency questionnaire) levels, and depression (Korean version of Beck’s Depression Inventory) and anxiety (State-Trait Anxiety Inventory) levels. To assess safety, adverse events, including laboratory test results, will be monitored. Further, the incremental cost-effectiveness ratio will be calculated based on quality-adjusted life years (from the EuroQoL five dimensions’ questionnaire) and medical expenses. Data will be statistically analyzed at a significance level of 0.05 (two-sided). This trial is registered with ClinicalTrials.gov NCT03219515, in July 2017

    Improvement of thermal hydrolysis rate of dichloroacetic acid using alcohol

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    Dichloroacetic acid (DCAA) is produced during the oxidation of trichloroethylene. It is also produced in drinking water treatment as a disinfection by-product. DCAA is a problem material, because of its toxicity. The objective of this research is to find the final products and the reaction pathway of the DCAA decomposition by hydrolysis, and to increase the hydrolysis rate. The removal of both chlorine atoms in DCAA structure was achieved with hydrolysis at around 75 °C, and the final products were oxalic acid and glycolic acid. The reaction pathway was the production of oxalic acid and glycolic acid from two glyoxylic acid molecules by Cannizzaro reaction after the glyoxylic acid production from dechlorination of DCAA with hydrolysis. The hydrolysis rate of DCAA was increased with the use of 90 1.140250e-268thanol solution as solvent. The activation energy of DCAA was about 80 kJ/mol in it, while it was around 105 kJ/mol in water
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